Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS1911 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- Mos (T93) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 61-110 of Human Mos.
- Description
- In each of these species, the c-Mos proto-oncogene locus consists of a single exon which encodes Mos, a serine/threonine protein kinase involved in the regulation of the meiotic cell cycle in vertebrate o?cytes. Mos function during o?cyte maturation is thought to be exerted through the stabilization or activation of the maturation promoting factor (MPF) complex. While the level of Mos expression is generally low in somatic cells, Mos is expressed at relatively high levels in germ cells. Mos can efficiently cause oncogenic transformation of somatic cells when ectopically expressed during the G1 phase of the cell cycle. Mos activates MAPK, possibly through direct phosphorylation of the MAPKK MEK-1.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of Mos (T93) pAb at 1:500 dilutionLane1:DLD whole cell lysateLane2:Raw264.7 whole cell lysateLane3:PC12 whole cell lysate