Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 10666-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10666-1-AP, RRID:AB_2166973
- Product name
- PMM2 antibody
- Antibody type
- Polyclonal
- Description
- PMM2 antibody (Cat. #10666-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Fatal outcome after heart surgery in PMM2-CDG due to a rare homozygous gene variant with double effects.
Repurposing the aldose reductase inhibitor and diabetic neuropathy drug epalrestat for the congenital disorder of glycosylation PMM2-CDG.
Novel variants and clinical symptoms in four new ALG3-CDG patients, review of the literature, and identification of AAGRP-ALG3 as a novel ALG3 variant with alanine and glycine-rich N-terminus.
Heterodimerization of Two Pathological Mutants Enhances the Activity of Human Phosphomannomutase2.
Lack of phosphomannomutase 2 affects Xenopus laevis morphogenesis and the non-canonical Wnt5a/Ror2 signalling.
Changes in the striatal proteome of YAC128Q mice exhibit gene-environment interactions between mutant huntingtin and manganese.
Görlacher M, Panagiotou E, Himmelreich N, Hüllen A, Beedgen L, Dimitrov B, Geiger V, Zielonka M, Peters V, Strahl S, Vázquez-Jiménez J, Kerst G, Thiel C
Molecular genetics and metabolism reports 2020 Dec;25:100673
Molecular genetics and metabolism reports 2020 Dec;25:100673
Repurposing the aldose reductase inhibitor and diabetic neuropathy drug epalrestat for the congenital disorder of glycosylation PMM2-CDG.
Iyer S, Sam FS, DiPrimio N, Preston G, Verheijen J, Murthy K, Parton Z, Tsang H, Lao J, Morava E, Perlstein EO
Disease models & mechanisms 2019 Nov 11;12(11)
Disease models & mechanisms 2019 Nov 11;12(11)
Novel variants and clinical symptoms in four new ALG3-CDG patients, review of the literature, and identification of AAGRP-ALG3 as a novel ALG3 variant with alanine and glycine-rich N-terminus.
Himmelreich N, Dimitrov B, Geiger V, Zielonka M, Hutter AM, Beedgen L, Hüllen A, Breuer M, Peters V, Thiemann KC, Hoffmann GF, Sinning I, Dupré T, Vuillaumier-Barrot S, Barrey C, Denecke J, Kölfen W, Düker G, Ganschow R, Lentze MJ, Moore S, Seta N, Ziegler A, Thiel C
Human mutation 2019 Jul;40(7):938-951
Human mutation 2019 Jul;40(7):938-951
Heterodimerization of Two Pathological Mutants Enhances the Activity of Human Phosphomannomutase2.
Andreotti G, Monti MC, Citro V, Cubellis MV
PloS one 2015;10(10):e0139882
PloS one 2015;10(10):e0139882
Lack of phosphomannomutase 2 affects Xenopus laevis morphogenesis and the non-canonical Wnt5a/Ror2 signalling.
Himmelreich N, Kaufmann LT, Steinbeisser H, Körner C, Thiel C
Journal of inherited metabolic disease 2015 Nov;38(6):1137-46
Journal of inherited metabolic disease 2015 Nov;38(6):1137-46
Changes in the striatal proteome of YAC128Q mice exhibit gene-environment interactions between mutant huntingtin and manganese.
Wegrzynowicz M, Holt HK, Friedman DB, Bowman AB
Journal of proteome research 2012 Feb 3;11(2):1118-32
Journal of proteome research 2012 Feb 3;11(2):1118-32
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 10666-1-AP(PMM2 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PMM2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PMM2. This antibody recognizes human,mouse,rat antigen. The PMM2 antibody has been validated for the following applications: ELISA, IHC, WB analysis.