Tissue expression
Cell line expression
Protein structure
MSH3
MutS homolog 3DUP, MRP1
The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011]
Top validated antibodies |
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Invitrogen Antibodies | PA5-29829 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
Proteintech Group | 22393-1-AP | 2 references | Polyclonal |
WB
EL
IP
|
|
Novus Biologicals | NBP2-19417 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
antibodies-online | ABIN968513 | 4 references | Monoclonal |
WB
ICC |
|
Affinity Biosciences | DF7457 | Polyclonal |
WB
EL
ICC
IHC |
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider