Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 13859-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13859-1-AP, RRID:AB_2204679
- Product name
- TIMM44 antibody
- Antibody type
- Polyclonal
- Description
- TIMM44 antibody (Cat. #13859-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Phosphorylation of Dynamin-Related Protein 1 (DRP1) Regulates Mitochondrial Dynamics and Skeletal Muscle Wasting in Cancer Cachexia.
LONP1 and mtHSP70 cooperate to promote mitochondrial protein folding.
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
Balancing of mitochondrial translation through METTL8-mediated m3C modification of mitochondrial tRNAs.
Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome.
The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis.
COX16 promotes COX2 metallation and assembly during respiratory complex IV biogenesis.
The phosphatase Pgam5 antagonizes Wnt/β-Catenin signaling in embryonic anterior-posterior axis patterning.
PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis.
Mitochondrial Protein Synthesis Adapts to Influx of Nuclear-Encoded Protein.
Translocase of inner mitochondrial membrane 44 alters the mitochondrial fusion and fission dynamics and protects from type 2 diabetes.
Mao X, Gu Y, Sui X, Shen L, Han J, Wang H, Xi Q, Zhuang Q, Meng Q, Wu G
Frontiers in cell and developmental biology 2021;9:673618
Frontiers in cell and developmental biology 2021;9:673618
LONP1 and mtHSP70 cooperate to promote mitochondrial protein folding.
Shin CS, Meng S, Garbis SD, Moradian A, Taylor RW, Sweredoski MJ, Lomenick B, Chan DC
Nature communications 2021 Jan 11;12(1):265
Nature communications 2021 Jan 11;12(1):265
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
Morgenstern M, Peikert CD, Lübbert P, Suppanz I, Klemm C, Alka O, Steiert C, Naumenko N, Schendzielorz A, Melchionda L, Mühlhäuser WWD, Knapp B, Busch JD, Stiller SB, Dannenmaier S, Lindau C, Licheva M, Eickhorst C, Galbusera R, Zerbes RM, Ryan MT, Kraft C, Kozjak-Pavlovic V, Drepper F, Dennerlein S, Oeljeklaus S, Pfanner N, Wiedemann N, Warscheid B
Cell metabolism 2021 Dec 7;33(12):2464-2483.e18
Cell metabolism 2021 Dec 7;33(12):2464-2483.e18
Balancing of mitochondrial translation through METTL8-mediated m3C modification of mitochondrial tRNAs.
Schöller E, Marks J, Marchand V, Bruckmann A, Powell CA, Reichold M, Mutti CD, Dettmer K, Feederle R, Hüttelmaier S, Helm M, Oefner P, Minczuk M, Motorin Y, Hafner M, Meister G
Molecular cell 2021 Dec 2;81(23):4810-4825.e12
Molecular cell 2021 Dec 2;81(23):4810-4825.e12
Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome.
Kang Y, Anderson AJ, Jackson TD, Palmer CS, De Souza DP, Fujihara KM, Stait T, Frazier AE, Clemons NJ, Tull D, Thorburn DR, McConville MJ, Ryan MT, Stroud DA, Stojanovski D
eLife 2019 Nov 4;8
eLife 2019 Nov 4;8
The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis.
Lavdovskaia E, Kolander E, Steube E, Mai MM, Urlaub H, Richter-Dennerlein R
Nucleic acids research 2018 Sep 19;46(16):8471-8482
Nucleic acids research 2018 Sep 19;46(16):8471-8482
COX16 promotes COX2 metallation and assembly during respiratory complex IV biogenesis.
Aich A, Wang C, Chowdhury A, Ronsör C, Pacheu-Grau D, Richter-Dennerlein R, Dennerlein S, Rehling P
eLife 2018 Jan 30;7
eLife 2018 Jan 30;7
The phosphatase Pgam5 antagonizes Wnt/β-Catenin signaling in embryonic anterior-posterior axis patterning.
Rauschenberger V, Bernkopf DB, Krenn S, Jalal K, Heller J, Behrens J, Gentzel M, Schambony A
Development (Cambridge, England) 2017 Jun 15;144(12):2234-2247
Development (Cambridge, England) 2017 Jun 15;144(12):2234-2247
PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis.
Saita S, Nolte H, Fiedler KU, Kashkar H, Venne AS, Zahedi RP, Krüger M, Langer T
Nature cell biology 2017 Apr;19(4):318-328
Nature cell biology 2017 Apr;19(4):318-328
Mitochondrial Protein Synthesis Adapts to Influx of Nuclear-Encoded Protein.
Richter-Dennerlein R, Oeljeklaus S, Lorenzi I, Ronsör C, Bareth B, Schendzielorz AB, Wang C, Warscheid B, Rehling P, Dennerlein S
Cell 2016 Oct 6;167(2):471-483.e10
Cell 2016 Oct 6;167(2):471-483.e10
Translocase of inner mitochondrial membrane 44 alters the mitochondrial fusion and fission dynamics and protects from type 2 diabetes.
Wang Y, Katayama A, Terami T, Han X, Nunoue T, Zhang D, Teshigawara S, Eguchi J, Nakatsuka A, Murakami K, Ogawa D, Furuta Y, Makino H, Wada J
Metabolism: clinical and experimental 2015 Jun;64(6):677-88
Metabolism: clinical and experimental 2015 Jun;64(6):677-88
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 13859-1-AP(TIMM44 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of A549 cells, using TIMM44 antibody 13859-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line