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antibody from antibodies-online
Targeting: RASA1
CM-AVM, GAP, p120, p120GAP, p120RASGAP, RASA
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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [2]
- ELISA [1]
- Immunohistochemistry [1]
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- Product number
- ABIN395417 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 948-1048) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 948-1048
- Isotype
- IgG
- Antibody clone number
- 2C12
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Backtracking RAS mutations in high hyperdiploid childhood acute lymphoblastic leukemia.
High-frequency type I/II mutational shifts between diagnosis and relapse are associated with outcome in pediatric AML: implications for personalized medicine.
Identification of several novel non-p.R132 IDH1 variants in thyroid carcinomas.
MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis.
A novel association between RASA1 mutations and spinal arteriovenous anomalies.
Wiemels JL, Kang M, Chang JS, Zheng L, Kouyoumji C, Zhang L, Smith MT, Scelo G, Metayer C, Buffler P, Wiencke JK
Blood cells, molecules & diseases 2010 Oct 15;45(3):186-91
Blood cells, molecules & diseases 2010 Oct 15;45(3):186-91
High-frequency type I/II mutational shifts between diagnosis and relapse are associated with outcome in pediatric AML: implications for personalized medicine.
Bachas C, Schuurhuis GJ, Hollink IH, Kwidama ZJ, Goemans BF, Zwaan CM, van den Heuvel-Eibrink MM, de Bont ES, Reinhardt D, Creutzig U, de Haas V, Assaraf YG, Kaspers GJ, Cloos J
Blood 2010 Oct 14;116(15):2752-8
Blood 2010 Oct 14;116(15):2752-8
Identification of several novel non-p.R132 IDH1 variants in thyroid carcinomas.
Hemerly JP, Bastos AU, Cerutti JM
European journal of endocrinology 2010 Nov;163(5):747-55
European journal of endocrinology 2010 Nov;163(5):747-55
MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis.
Anand S, Majeti BK, Acevedo LM, Murphy EA, Mukthavaram R, Scheppke L, Huang M, Shields DJ, Lindquist JN, Lapinski PE, King PD, Weis SM, Cheresh DA
Nature medicine 2010 Aug;16(8):909-14
Nature medicine 2010 Aug;16(8):909-14
A novel association between RASA1 mutations and spinal arteriovenous anomalies.
Thiex R, Mulliken JB, Revencu N, Boon LM, Burrows PE, Cordisco M, Dwight Y, Smith ER, Vikkula M, Orbach DB
AJNR. American journal of neuroradiology 2010 Apr;31(4):775-9
AJNR. American journal of neuroradiology 2010 Apr;31(4):775-9
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Supportive validation
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- ELISA
Supportive validation
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- IHC
