Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [6]
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Validation data
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- Product number
- NBP1-88595 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-88595, RRID:AB_11014588
- Product name
- Rabbit Polyclonal PTRH2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human PTRH2 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references The anoikis effector Bit1 displays tumor suppressive function in lung cancer cells.
TLE1 is an anoikis regulator and is downregulated by Bit1 in breast cancer cells.
Metastasis of tumor cells is enhanced by downregulation of Bit1.
Yao X, Jennings S, Ireland SK, Pham T, Temple B, Davis M, Chen R, Davenport I, Biliran H
PloS one 2014;9(7):e101564
PloS one 2014;9(7):e101564
TLE1 is an anoikis regulator and is downregulated by Bit1 in breast cancer cells.
Brunquell C, Biliran H, Jennings S, Ireland SK, Chen R, Ruoslahti E
Molecular cancer research : MCR 2012 Nov;10(11):1482-95
Molecular cancer research : MCR 2012 Nov;10(11):1482-95
Metastasis of tumor cells is enhanced by downregulation of Bit1.
Karmali PP, Brunquell C, Tram H, Ireland SK, Ruoslahti E, Biliran H
PloS one 2011;6(8):e23840
PloS one 2011;6(8):e23840
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: PTRH2 Antibody [NBP1-88595] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-451
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: PTRH2 Antibody [NBP1-88595] - Staining of human colon shows strong cytoplasmic positivity, with a granular pattern, in glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: PTRH2 Antibody [NBP1-88595] - Staining of human epididymis shows strong cytoplasmic positivity in glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: PTRH2 Antibody [NBP1-88595] - Staining of human liver shows strong granular cytoplasmic positivity in hepatocytes.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: PTRH2 Antibody [NBP1-88595] - Staining of human skeletal muscle shows moderate cytoplasmic positivity in myocytes.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: PTRH2 Antibody [NBP1-88595] - Staining of human small intestine shows strong granular cytoplasmic positivity in glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: PTRH2 Antibody [NBP1-88595] - Staining of human testis shows strong granular cytoplasmic positivity in cells in seminiferous ducts.