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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN1882153 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2) (C-Term), (AA 399-427) antibody
- Antibody type
- Polyclonal
- Antigen
- This YARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-427 amino acids from the C-terminal region of human YARS2.
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- C-Term,AA 399-427
- Antibody clone number
- RB14936
- Vial size
- 400 μL
- Concentration
- 2 mg/mL
Submitted references Phenotypic variability and identification of novel YARS2 mutations in YARS2 mitochondrial myopathy, lactic acidosis and sideroblastic anaemia.
Mutation of the mitochondrial tyrosyl-tRNA synthetase gene, YARS2, causes myopathy, lactic acidosis, and sideroblastic anemia--MLASA syndrome.
Crystal structure of human mitochondrial tyrosyl-tRNA synthetase reveals common and idiosyncratic features.
Riley LG, Menezes MJ, Rudinger-Thirion J, Duff R, de Lonlay P, Rotig A, Tchan MC, Davis M, Cooper ST, Christodoulou J
Orphanet journal of rare diseases 2013 Dec 17;8:193
Orphanet journal of rare diseases 2013 Dec 17;8:193
Mutation of the mitochondrial tyrosyl-tRNA synthetase gene, YARS2, causes myopathy, lactic acidosis, and sideroblastic anemia--MLASA syndrome.
Riley LG, Cooper S, Hickey P, Rudinger-Thirion J, McKenzie M, Compton A, Lim SC, Thorburn D, Ryan MT, Giegé R, Bahlo M, Christodoulou J
American journal of human genetics 2010 Jul 9;87(1):52-9
American journal of human genetics 2010 Jul 9;87(1):52-9
Crystal structure of human mitochondrial tyrosyl-tRNA synthetase reveals common and idiosyncratic features.
Bonnefond L, Frugier M, Touzé E, Lorber B, Florentz C, Giegé R, Sauter C, Rudinger-Thirion J
Structure (London, England : 1993) 2007 Nov;15(11):1505-16
Structure (London, England : 1993) 2007 Nov;15(11):1505-16
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of anti-YARS2 Antibody (C-term) (ABIN1882153) in CEM cell line lysates (35 μg/lane). YARS(arrow) was detected using the purified Pab.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of anti-YARS2 Antibody (C-term) (ABIN1882153) in CEM cell line lysates (35 μg/lane). YARS(arrow) was detected using the purified Pab.
