FNab09557

antibody from FineTest Biotech

Targeting: XRN2

Western blot

ELISA

Antibody data

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Validation data

Product number: FNab09557 - Provider product page
Provider: FineTest Biotech
Product name: XRN2 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Possesses 5'->3' exoribonuclease activity(By similarity). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II(RNAp II) transcription termination R-loops formed by G-rich pause sites(PubMed:21700224).
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: 5'-3' exoribonuclease 2
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

XRN2 protein structure - FNab09557 shown in red.