V2495
antibody from NSJ Bioreagents
Targeting: FCGR2A
CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Other assay [1]
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Validation data
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- Product number
- V2495 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- CD32 Antibody
- Antibody type
- Monoclonal
- Antigen
- K562 and FcgRII+L cells were used as the immunogen for the CD32 antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- 7.3
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the CD32 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Effect of trastuzumab interchain disulfide bond cleavage on Fcγ receptor binding and antibody-dependent tumour cell phagocytosis.
C-reactive protein enhances IgG-mediated phagocyte responses and thrombocytopenia.
Inhibition of FcγR-mediated phagocytosis by IVIg is independent of IgG-Fc sialylation and FcγRIIb in human macrophages.
Activation of human synovial mast cells from rheumatoid arthritis or osteoarthritis patients in response to aggregated IgG through Fcγ receptor I and Fcγ receptor II.
The pro-atherogenic effects of macrophages are reduced upon formation of a complex between C-reactive protein and lysophosphatidylcholine.
Suzuki M, Yamanoi A, Machino Y, Ootsubo M, Izawa K, Kohroki J, Masuho Y
Journal of biochemistry 2016 Jan;159(1):67-76
Journal of biochemistry 2016 Jan;159(1):67-76
C-reactive protein enhances IgG-mediated phagocyte responses and thrombocytopenia.
Kapur R, Heitink-Pollé KM, Porcelijn L, Bentlage AE, Bruin MC, Visser R, Roos D, Schasfoort RB, de Haas M, van der Schoot CE, Vidarsson G
Blood 2015 Mar 12;125(11):1793-802
Blood 2015 Mar 12;125(11):1793-802
Inhibition of FcγR-mediated phagocytosis by IVIg is independent of IgG-Fc sialylation and FcγRIIb in human macrophages.
Nagelkerke SQ, Dekkers G, Kustiawan I, van de Bovenkamp FS, Geissler J, Plomp R, Wuhrer M, Vidarsson G, Rispens T, van den Berg TK, Kuijpers TW
Blood 2014 Dec 11;124(25):3709-18
Blood 2014 Dec 11;124(25):3709-18
Activation of human synovial mast cells from rheumatoid arthritis or osteoarthritis patients in response to aggregated IgG through Fcγ receptor I and Fcγ receptor II.
Lee H, Kashiwakura J, Matsuda A, Watanabe Y, Sakamoto-Sasaki T, Matsumoto K, Hashimoto N, Saito S, Ohmori K, Nagaoka M, Tokuhashi Y, Ra C, Okayama Y
Arthritis and rheumatism 2013 Jan;65(1):109-19
Arthritis and rheumatism 2013 Jan;65(1):109-19
The pro-atherogenic effects of macrophages are reduced upon formation of a complex between C-reactive protein and lysophosphatidylcholine.
Chang MK, Hartvigsen K, Ryu J, Kim Y, Han KH
Journal of inflammation (London, England) 2012 Oct 31;9(1):42
Journal of inflammation (London, England) 2012 Oct 31;9(1):42
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- SDS-PAGE Analysis of Purified, BSA-Free CD32 Antibody (clone 7.3). Confirmation of Integrity and Purity of the Antibody.