BCL2L10

gene product
BCL-B, Boo, Diva
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
227 antibodies from 32 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Invitrogen Antibodies
5 antibodies
Novus Biologicals
8 antibodies
antibodies-online
67 antibodies
OriGene
3 antibodies
LifeSpan BioSciences, Inc.
34 antibodies
Abnova Corporation
6 antibodies
GeneTex
3 antibodies
Biorbyt
10 antibodies
Aviva Systems Biology
1 antibody
Proteintech Group
1 antibody
Signalway Antibody LLC
1 antibody
Acris Antibodies GmbH
7 antibodies
Affinity Biosciences
1 antibody
NovoPro Bioscience Inc.
1 antibody
Abgent
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
ProSci
1 antibody
Creative Biolabs
7 antibodies
RabMAbs
2 antibodies
Atlas Antibodies
1 antibody
MyBioSource
4 antibodies
Leading Biology
4 antibodies
Creative Diagnostics
4 antibodies
Abbiotec
1 antibody
Cell Signaling Technology, Inc
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
RayBiotech, Inc.
3 antibodies
Sigma-Aldrich
2 antibodies
United States Biological
27 antibodies
EMD Millipore
1 antibody
St John's Laboratory
1 antibody