CABT-B10894
antibody from Creative Diagnostics
Targeting: PATZ1
dJ400N23, MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- CABT-B10894 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse anti-Human PATZ1 monoclonal antibody, clone 2C3
- Antibody type
- Monoclonal
- Description
- The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1
No comments: Submit comment
No validations: Submit validation data