CABT-B10894

antibody from Creative Diagnostics

Targeting: PATZ1 dJ400N23, MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG

No application information provided.

Antibody Data

Product number

CABT-B10894

Provider

Creative Diagnostics

Product name

Mouse anti-Human PATZ1 monoclonal antibody, clone 2C3

Antibody type

Monoclonal

Description

The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1