BS8641

antibody from Bioworld Technology, Inc
Targeting: MANF ARMET, ARP
Provider product page for BS8641
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8641 - Provider product page
Provider
Bioworld Technology, Inc
Product name
MANF polyclonal antibody
Antibody type
Polyclonal
Antigen
Mesencephalic astrocyte-derived neurotrophic factor; Arginine-rich protein; Protein ARMET; MANF; ARMET, ARP
Description
The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MANF protein structure - BS8641 shown in red.