AP0313

antibody from Bioworld Technology, Inc
Targeting: CD226 DNAM-1, DNAM1, PTA1, TLiSA1
Provider product page for AP0313

Antibody data

Product number
AP0313 - Provider product page
Provider
Bioworld Technology, Inc
Product name
DNAM 1 (phospho S329) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human DNAM 1 around the phosphorylation site of Serine 329.
Description
DNAM 1 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CD226 protein structure - AP0313 shown in red.