Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-BL7117 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-CD226 Monoclonal antibody, clone 2F7
- Antibody type
- Monoclonal
- Description
- DNAM 1 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.
- Reactivity
- Mouse
- Host
- Rat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2F7
- Vial size
- 50 ug
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