GTX74290

antibody from GeneTex

Targeting: TGOLN2 TGN38, TGN46, TGN48, TGN51, TTGN2

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

GTX74290

Provider

GeneTex

Proper citation

GeneTex Cat#GTX74290, RRID:AB_1952846

Product name

TGN46 antibody

Antibody type

Polyclonal

Reactivity

Human

Host

Sheep

References

Submitted references

SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion.

McGough IJ, de Groot REA, Jellett AP, Betist MC, Varandas KC, Danson CM, Heesom KJ, Korswagen HC, Cullen PJ
Nature communications 2018 Sep 13;9(1):3737

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Sorting nexin-21 is a scaffold for the endosomal recruitment of huntingtin.

Danson CM, Pearson N, Heesom KJ, Cullen PJ
Journal of cell science 2018 Sep 10;131(17)

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Abnormal glycosylation in Joubert syndrome type 10.

Kane MS, Davids M, Bond MR, Adams CJ, Grout ME, Phelps IG, O'Day DR, Dempsey JC, Li X, Golas G, Vezina G, Gunay-Aygun M, Hanover JA, Doherty D, He M, Malicdan MCV, Gahl WA, Boerkoel CF
Cilia 2017;6:2

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Disruption of Golgi morphology and altered protein glycosylation in PLA2G6-associated neurodegeneration.

Davids M, Kane MS, He M, Wolfe LA, Li X, Raihan MA, Chao KR, Bone WP, Boerkoel CF, Gahl WA, Toro C
Journal of medical genetics 2016 Mar;53(3):180-9

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Neuronal differentiation is associated with a redox-regulated increase of copper flow to the secretory pathway.

Hatori Y, Yan Y, Schmidt K, Furukawa E, Hasan NM, Yang N, Liu CN, Sockanathan S, Lutsenko S
Nature communications 2016 Feb 16;7:10640

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Genome-wide RNAi ionomics screen reveals new genes and regulation of human trace element metabolism.

Malinouski M, Hasan NM, Zhang Y, Seravalli J, Lin J, Avanesov A, Lutsenko S, Gladyshev VN
Nature communications 2014;5:3301

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Diverse functional properties of Wilson disease ATP7B variants.

Huster D, Kühne A, Bhattacharjee A, Raines L, Jantsch V, Noe J, Schirrmeister W, Sommerer I, Sabri O, Berr F, Mössner J, Stieger B, Caca K, Lutsenko S
Gastroenterology 2012 Apr;142(4):947-956.e5

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Difference in stability of the N-domain underlies distinct intracellular properties of the E1064A and H1069Q mutants of copper-transporting ATPase ATP7B.

Dmitriev OY, Bhattacharjee A, Nokhrin S, Uhlemann EM, Lutsenko S
The Journal of biological chemistry 2011 May 6;286(18):16355-62

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SOCS1 is an inducible host factor during HIV-1 infection and regulates the intracellular trafficking and stability of HIV-1 Gag.

Ryo A, Tsurutani N, Ohba K, Kimura R, Komano J, Nishi M, Soeda H, Hattori S, Perrem K, Yamamoto M, Chiba J, Mimaya J, Yoshimura K, Matsushita S, Honda M, Yoshimura A, Sawasaki T, Aoki I, Morikawa Y, Yamamoto N
Proceedings of the National Academy of Sciences of the United States of America 2008 Jan 8;105(1):294-9