FNab02974

antibody from FineTest Biotech

Targeting: ABRAXAS1 ABRA1, ABRAXAS, CCDC98, FAM175A, FLJ13614

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ELISA

Immunocytochemistry

Immunohistochemistry

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Validation data

Product number: FNab02974 - Provider product page
Provider: FineTest Biotech
Product name: FAM175A antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Involved in DNA damage response and double-strand break(DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: family with sequence similarity 175 , member A
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

ABRAXAS1 protein structure - FNab02974 shown in red.