abx026681

antibody from Abbexa

Targeting: SNX13 KIAA0713, RGS-PX1

No application information provided.

Antibody Data

Product number

abx026681

Provider

Abbexa

Product name

Sorting Nexin 13 (SNX13) Antibody

Antibody type

Polyclonal

Description

This gene encodes a PHOX domain and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha (s), accelerates its GTP hydrolysis, and attenuates G alpha (s) mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

80 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.