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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- PAB3134 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB3134, RRID:AB_1571096
- Product name
- ALDH5A1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of ALDH5A1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Therapeutic concepts in succinate semialdehyde dehydrogenase (SSADH; ALDH5a1) deficiency (gamma-hydroxybutyric aciduria). Hypotheses evolved from 25 years of patient evaluation, studies in Aldh5a1-/- mice and characterization of gamma-hydroxybutyric acid pharmacology.
SSADH variation in primates: intra- and interspecific data on a gene with a potential role in human cognitive functions.
A functional polymorphism in the succinate-semialdehyde dehydrogenase (aldehyde dehydrogenase 5 family, member A1) gene is associated with cognitive ability.
Knerr I, Pearl PL, Bottiglieri T, Snead OC, Jakobs C, Gibson KM
Journal of inherited metabolic disease 2007 Jun;30(3):279-94
Journal of inherited metabolic disease 2007 Jun;30(3):279-94
SSADH variation in primates: intra- and interspecific data on a gene with a potential role in human cognitive functions.
Blasi P, Palmerio F, Aiello A, Rocchi M, Malaspina P, Novelletto A
Journal of molecular evolution 2006 Jul;63(1):54-68
Journal of molecular evolution 2006 Jul;63(1):54-68
A functional polymorphism in the succinate-semialdehyde dehydrogenase (aldehyde dehydrogenase 5 family, member A1) gene is associated with cognitive ability.
Plomin R, Turic DM, Hill L, Turic DE, Stephens M, Williams J, Owen MJ, O'Donovan MC
Molecular psychiatry 2004 Jun;9(6):582-6
Molecular psychiatry 2004 Jun;9(6):582-6
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of ALDH5A1 (arrow) using rabbit ALDH5A1 polyclonal antibody (Cat # PAB3134). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ALDH5A1 gene (Lane 2) (Origene Technologies).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma reacted with ALDH5A1 polyclonal antibody (Cat # PAB3134) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Flow cytometric analysis of ATDC5 cells using ALDH5A1 polyclonal antibody (Cat # PAB3134)(bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
- Validation comment
- Flow Cytometry
