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- Antibody Data
- Antigen structure
- References [36]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12348-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12348-1-AP, RRID:AB_2100341
- Product name
- FABP5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FABP5 antibody (Cat. #12348-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Lipid overload-induced RTN3 activation leads to cardiac dysfunction by promoting lipid droplet biogenesis.
Podophyllotoxin via SIRT1/PPAR /NF-κB axis induced cardiac injury in rats based on the toxicological evidence chain (TEC) concept.
High levels of fatty acid-binding protein 5 excessively enhances fatty acid synthesis and proliferation of granulosa cells in polycystic ovary syndrome.
Doxorubicin resistance in breast cancer is mediated via the activation of FABP5/PPARγ and CaMKII signaling pathway.
A transient wave of Bhlhe41(+) resident macrophages enables remodeling of the developing infarcted myocardium.
L-theanine regulates the immune function of SD rats fed high-protein diets through the FABP5/IL-6/STAT3/PPARα pathway.
L-Theanine Mitigates the Harmful Effects of Excess High-Protein Diet in Rats by Regulating Protein Metabolism.
IGF2 May Enhance Placental Fatty Acid Metabolism by Regulating Expression of Fatty Acid Carriers in the Growth of Fetus and Placenta during Late Pregnancy in Pigs.
Effects of Fatty Acids on Proliferation of Cultured Wild-type and FABP5-KO Thymic Epithelial Cells.
Fatty acid-binding protein 5 aggravates pulmonary artery fibrosis in pulmonary hypertension secondary to left heart disease via activating wnt/β-catenin pathway.
Lipid-lowering activity of metformin-soluble soybean polysaccharide nanoparticles.
Adenosine-rich extract of Ganoderma lucidum: A safe and effective lipid-lowering substance.
Fatty acid binding protein 5 promotes the proliferation, migration, and invasion of hepatocellular carcinoma cells by degradation of Krüppel-like factor 9 mediated by miR-889-5p via cAMP-response element binding protein.
Soybean soluble polysaccharide prevents obesity in high-fat diet-induced rats via lipid metabolism regulation.
Peroxisomal Fatty Acid Oxidation and Glycolysis Are Triggered in Mouse Models of Lesional Atopic Dermatitis.
MMP-12 siRNA improves the homeostasis of the small intestine and metabolic dysfunction in high-fat diet feeding-induced obese mice.
Heparin-Binding Protein 17/Fibroblast Growth Factor-Binding Protein-1 Knockout Inhibits Proliferation and Induces Differentiation of Squamous Cell Carcinoma Cells.
Differentially expressed proteins identified by TMT proteomics analysis in children with verrucous epidermal naevi.
Oxidative stress-induced FABP5 S-glutathionylation protects against acute lung injury by suppressing inflammation in macrophages.
Proteome characteristics of liver tissue from patients with parenteral nutrition-associated liver disease.
Single-Cell Transcriptome Analysis Reveals Intratumoral Heterogeneity in ccRCC, which Results in Different Clinical Outcomes.
Deregulating the CYP2C19/Epoxy-Eicosatrienoic Acid-Associated FABP4/FABP5 Signaling Network as a Therapeutic Approach for Metastatic Triple-Negative Breast Cancer.
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.
FABP5 is correlated with poor prognosis and promotes tumour cell growth and metastasis in clear cell renal cell carcinoma.
Lysine Enhances the Stimulation of Fatty Acids on Milk Fat Synthesis via the GPRC6A-PI3K-FABP5 Signaling in Bovine Mammary Epithelial Cells.
Fatty-acid binding protein 5 modulates the SAR1 GTPase cycle and enhances budding of large COPII cargoes.
Resveratrol Suppresses the Growth and Enhances Retinoic Acid Sensitivity of Anaplastic Thyroid Cancer Cells.
The natural compound GL22, isolated from Ganoderma mushrooms, suppresses tumor growth by altering lipid metabolism and triggering cell death.
Differential CRABP-II and FABP5 expression patterns and implications for medulloblastoma retinoic acid sensitivity.
Dual Inhibition of PI3K/Akt and mTOR by the Dietary Antioxidant, Delphinidin, Ameliorates Psoriatic Features In Vitro and in an Imiquimod-Induced Psoriasis-Like Disease in Mice.
Differential Proteomic Analysis of Gender-dependent Hepatic Tumorigenesis in Hras12V Transgenic Mice.
CRABP-II- and FABP5-independent responsiveness of human glioblastoma cells to all-trans retinoic acid.
Allergen-induced dermatitis causes alterations in cutaneous retinoid-mediated signaling in mice.
E-FABP induces differentiation in normal human keratinocytes and modulates the differentiation process in psoriatic keratinocytes in vitro.
CRABP-II- and FABP5-independent all-trans retinoic acid resistance in COLO 16 human cutaneous squamous cancer cells.
Identification of potential therapeutic targets in human head & neck squamous cell carcinoma.
Guo D, Zhang M, Qi B, Peng T, Liu M, Li Z, Fu F, Guo Y, Li C, Wang Y, Hu L, Li Y
Cell death and differentiation 2024 Mar;31(3):292-308
Cell death and differentiation 2024 Mar;31(3):292-308
Podophyllotoxin via SIRT1/PPAR /NF-κB axis induced cardiac injury in rats based on the toxicological evidence chain (TEC) concept.
Jiang T, Sun L, Wang Y, Zhang F, Guo J, Sun L, Jiang Y, Xue J, Duan J, Liu C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155655
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155655
High levels of fatty acid-binding protein 5 excessively enhances fatty acid synthesis and proliferation of granulosa cells in polycystic ovary syndrome.
Liu J, Li J, Wu X, Zhang M, Yan G, Sun H, Li D
Journal of ovarian research 2024 Feb 19;17(1):44
Journal of ovarian research 2024 Feb 19;17(1):44
Doxorubicin resistance in breast cancer is mediated via the activation of FABP5/PPARγ and CaMKII signaling pathway.
Chen NN, Ma XD, Miao Z, Zhang XM, Han BY, Almaamari AA, Huang JM, Chen XY, Liu YJ, Su SW
Frontiers in pharmacology 2023;14:1150861
Frontiers in pharmacology 2023;14:1150861
A transient wave of Bhlhe41(+) resident macrophages enables remodeling of the developing infarcted myocardium.
Xu Y, Jiang K, Su F, Deng R, Cheng Z, Wang D, Yu Y, Xiang Y
Cell reports 2023 Oct 31;42(10):113174
Cell reports 2023 Oct 31;42(10):113174
L-theanine regulates the immune function of SD rats fed high-protein diets through the FABP5/IL-6/STAT3/PPARα pathway.
Zhang Y, Song Y, Zhang J, Li L, He L, Bo J, Gong Z, Xiao W
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114095
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114095
L-Theanine Mitigates the Harmful Effects of Excess High-Protein Diet in Rats by Regulating Protein Metabolism.
Lin L, Zhang J, He L, Li L, Song Y, Xiao W, Gong Z
Molecular nutrition & food research 2023 Jan;67(2):e2200198
Molecular nutrition & food research 2023 Jan;67(2):e2200198
IGF2 May Enhance Placental Fatty Acid Metabolism by Regulating Expression of Fatty Acid Carriers in the Growth of Fetus and Placenta during Late Pregnancy in Pigs.
Wu Z, Hu G, Zhang Y, Ao Z
Genes 2023 Apr 5;14(4)
Genes 2023 Apr 5;14(4)
Effects of Fatty Acids on Proliferation of Cultured Wild-type and FABP5-KO Thymic Epithelial Cells.
Adachi Y
Journal of UOEH 2022;44(3):239-248
Journal of UOEH 2022;44(3):239-248
Fatty acid-binding protein 5 aggravates pulmonary artery fibrosis in pulmonary hypertension secondary to left heart disease via activating wnt/β-catenin pathway.
Lei Q, Yu Z, Li H, Cheng J, Wang Y
Journal of advanced research 2022 Sep;40:197-206
Journal of advanced research 2022 Sep;40:197-206
Lipid-lowering activity of metformin-soluble soybean polysaccharide nanoparticles.
He H, Liu M, He R, Zhao W
Food & function 2022 Oct 3;13(19):10265-10274
Food & function 2022 Oct 3;13(19):10265-10274
Adenosine-rich extract of Ganoderma lucidum: A safe and effective lipid-lowering substance.
Li H, Du Y, Ji H, Yang Y, Xu C, Li Q, Ran L, Wu C, Zhou Q, Wu S
iScience 2022 Nov 18;25(11):105214
iScience 2022 Nov 18;25(11):105214
Fatty acid binding protein 5 promotes the proliferation, migration, and invasion of hepatocellular carcinoma cells by degradation of Krüppel-like factor 9 mediated by miR-889-5p via cAMP-response element binding protein.
Tang Y, Li K, Hu B, Cai Z, Li J, Tao H, Cao J
Cancer biology & therapy 2022 Dec 31;23(1):424-438
Cancer biology & therapy 2022 Dec 31;23(1):424-438
Soybean soluble polysaccharide prevents obesity in high-fat diet-induced rats via lipid metabolism regulation.
He H, Chen C, Zhao W
International journal of biological macromolecules 2022 Dec 1;222(Pt B):3057-3065
International journal of biological macromolecules 2022 Dec 1;222(Pt B):3057-3065
Peroxisomal Fatty Acid Oxidation and Glycolysis Are Triggered in Mouse Models of Lesional Atopic Dermatitis.
Pavel P, Leman G, Hermann M, Ploner C, Eichmann TO, Minzaghi D, Radner FPW, Del Frari B, Gruber R, Dubrac S
JID innovations : skin science from molecules to population health 2021 Sep;1(3):100033
JID innovations : skin science from molecules to population health 2021 Sep;1(3):100033
MMP-12 siRNA improves the homeostasis of the small intestine and metabolic dysfunction in high-fat diet feeding-induced obese mice.
Song M, Zhang S, Tao Z, Li J, Shi Y, Xiong Y, Zhang W, Liu C, Chen S
Biomaterials 2021 Nov;278:121183
Biomaterials 2021 Nov;278:121183
Heparin-Binding Protein 17/Fibroblast Growth Factor-Binding Protein-1 Knockout Inhibits Proliferation and Induces Differentiation of Squamous Cell Carcinoma Cells.
Shintani T, Higaki M, Okamoto T
Cancers 2021 May 29;13(11)
Cancers 2021 May 29;13(11)
Differentially expressed proteins identified by TMT proteomics analysis in children with verrucous epidermal naevi.
Yuan T, Cai ML, Sheng YM, Ding X, Shen TT, Li WR, Huang H, Liang B, Zhang XJ, Zhu QX
Journal of the European Academy of Dermatology and Venereology : JEADV 2021 Jun;35(6):1393-1406
Journal of the European Academy of Dermatology and Venereology : JEADV 2021 Jun;35(6):1393-1406
Oxidative stress-induced FABP5 S-glutathionylation protects against acute lung injury by suppressing inflammation in macrophages.
Guo Y, Liu Y, Zhao S, Xu W, Li Y, Zhao P, Wang D, Cheng H, Ke Y, Zhang X
Nature communications 2021 Dec 7;12(1):7094
Nature communications 2021 Dec 7;12(1):7094
Proteome characteristics of liver tissue from patients with parenteral nutrition-associated liver disease.
Maitiabola G, Tian F, Sun H, Zhang L, Gao X, Xue B, Wang X
Nutrition & metabolism 2020;17:43
Nutrition & metabolism 2020;17:43
Single-Cell Transcriptome Analysis Reveals Intratumoral Heterogeneity in ccRCC, which Results in Different Clinical Outcomes.
Hu J, Chen Z, Bao L, Zhou L, Hou Y, Liu L, Xiong M, Zhang Y, Wang B, Tao Z, Chen K
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jul 8;28(7):1658-1672
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jul 8;28(7):1658-1672
Deregulating the CYP2C19/Epoxy-Eicosatrienoic Acid-Associated FABP4/FABP5 Signaling Network as a Therapeutic Approach for Metastatic Triple-Negative Breast Cancer.
Apaya MK, Hsiao PW, Yang YC, Shyur LF
Cancers 2020 Jan 13;12(1)
Cancers 2020 Jan 13;12(1)
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.
Zhang Y, Li C, Hu C, Wu Q, Cai Y, Xing S, Lu H, Wang L, Huang D, Sun L, Li T, He X, Zhong X, Wang J, Gao P, Smith ZJ, Jia W, Zhang H
EMBO reports 2019 Oct 4;20(10):e48115
EMBO reports 2019 Oct 4;20(10):e48115
FABP5 is correlated with poor prognosis and promotes tumour cell growth and metastasis in clear cell renal cell carcinoma.
Wu G, Xu Y, Wang Q, Li J, Li L, Han C, Xia Q
European journal of pharmacology 2019 Nov 5;862:172637
European journal of pharmacology 2019 Nov 5;862:172637
Lysine Enhances the Stimulation of Fatty Acids on Milk Fat Synthesis via the GPRC6A-PI3K-FABP5 Signaling in Bovine Mammary Epithelial Cells.
Li X, Li P, Wang L, Zhang M, Gao X
Journal of agricultural and food chemistry 2019 Jun 26;67(25):7005-7015
Journal of agricultural and food chemistry 2019 Jun 26;67(25):7005-7015
Fatty-acid binding protein 5 modulates the SAR1 GTPase cycle and enhances budding of large COPII cargoes.
Melville D, Gorur A, Schekman R
Molecular biology of the cell 2019 Feb 1;30(3):387-399
Molecular biology of the cell 2019 Feb 1;30(3):387-399
Resveratrol Suppresses the Growth and Enhances Retinoic Acid Sensitivity of Anaplastic Thyroid Cancer Cells.
Li YT, Tian XT, Wu ML, Zheng X, Kong QY, Cheng XX, Zhu GW, Liu J, Li H
International journal of molecular sciences 2018 Mar 29;19(4)
International journal of molecular sciences 2018 Mar 29;19(4)
The natural compound GL22, isolated from Ganoderma mushrooms, suppresses tumor growth by altering lipid metabolism and triggering cell death.
Liu G, Wang K, Kuang S, Cao R, Bao L, Liu R, Liu H, Sun C
Cell death & disease 2018 Jun 7;9(6):689
Cell death & disease 2018 Jun 7;9(6):689
Differential CRABP-II and FABP5 expression patterns and implications for medulloblastoma retinoic acid sensitivity.
Zhang S, Liu H, Li H, Wu M, Yu Y, Li F, Cheng X
RSC advances 2018 Apr 11;8(25):14048-14055
RSC advances 2018 Apr 11;8(25):14048-14055
Dual Inhibition of PI3K/Akt and mTOR by the Dietary Antioxidant, Delphinidin, Ameliorates Psoriatic Features In Vitro and in an Imiquimod-Induced Psoriasis-Like Disease in Mice.
Chamcheu JC, Adhami VM, Esnault S, Sechi M, Siddiqui IA, Satyshur KA, Syed DN, Dodwad SM, Chaves-Rodriquez MI, Longley BJ, Wood GS, Mukhtar H
Antioxidants & redox signaling 2017 Jan 10;26(2):49-69
Antioxidants & redox signaling 2017 Jan 10;26(2):49-69
Differential Proteomic Analysis of Gender-dependent Hepatic Tumorigenesis in Hras12V Transgenic Mice.
Rong Z, Fan T, Li H, Li J, Wang K, Wang X, Dong J, Chen J, Wang F, Wang J, Wang A
Molecular & cellular proteomics : MCP 2017 Aug;16(8):1475-1490
Molecular & cellular proteomics : MCP 2017 Aug;16(8):1475-1490
CRABP-II- and FABP5-independent responsiveness of human glioblastoma cells to all-trans retinoic acid.
Xia SL, Wu ML, Li H, Wang JH, Chen NN, Chen XY, Kong QY, Sun Z, Liu J
Oncotarget 2015 Mar 20;6(8):5889-902
Oncotarget 2015 Mar 20;6(8):5889-902
Allergen-induced dermatitis causes alterations in cutaneous retinoid-mediated signaling in mice.
Gericke J, Ittensohn J, Mihály J, Dubrac S, Rühl R
PloS one 2013;8(8):e71244
PloS one 2013;8(8):e71244
E-FABP induces differentiation in normal human keratinocytes and modulates the differentiation process in psoriatic keratinocytes in vitro.
Dallaglio K, Marconi A, Truzzi F, Lotti R, Palazzo E, Petrachi T, Saltari A, Coppini M, Pincelli C
Experimental dermatology 2013 Apr;22(4):255-61
Experimental dermatology 2013 Apr;22(4):255-61
CRABP-II- and FABP5-independent all-trans retinoic acid resistance in COLO 16 human cutaneous squamous cancer cells.
Chen NN, Li Y, Wu ML, Liu ZL, Fu YS, Kong QY, Chen XY, Li H, Liu J
Experimental dermatology 2012 Jan;21(1):13-8
Experimental dermatology 2012 Jan;21(1):13-8
Identification of potential therapeutic targets in human head & neck squamous cell carcinoma.
Han J, Kioi M, Chu WS, Kasperbauer JL, Strome SE, Puri RK
Head & neck oncology 2009 Jul 14;1:27
Head & neck oncology 2009 Jul 14;1:27
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 12348-1-AP(FABP5 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FABP5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FABP5. This antibody recognizes human,mouse,rat antigen. The FABP5 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
