BS2281

antibody from Bioworld Technology, Inc
Targeting: DGKE DAGK6, DGK
Provider product page for BS2281
Western blot
Immunohistochemistry

Antibody data

Product number
BS2281 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS2281, RRID:AB_1662778
Product name
DGK š÷ (S194) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 180-230 of Human DGK-š÷.
Description
Diacylglycerol (DAG) influences numerous cell signaling cascades by functioning as an intracellular, allosteric activator of protein kinase C (PKC), and as a potent activator of guanine nucleotide exchange factors. In order to maintain cellular homeostasis, intracellular DAG levels are tightly regulated by diacylglycerol kinases (DGKs, DAGKs), which phosphorylate DAG to phosphatidic acid, thus removing DAG. Human DGK-Ï« (80 kDa), -ÉÇ (90 kDa), and -ÎÛ (90 kDa) have calcium-binding EF-hand motifs at their N termini and are classified as type I DGKs. Human DGK-Ñ´ (130 kDa) and DGK-i (130 kDa) contain N-terminal pleckstrin homology (PH) domains and are classified as type II. Human DGK-š÷ (64 kDa) contains no identifiable regulatory domains and is classified as a type III DGK. Human DGK-šø (104 kDa) and -iota (130 kDa) possess C-terminal ankyrin repeats and are classified as type IV DGKs. Human DGK-IJ (110 kDa) contains 3 cysteine-rich domains and a PH domain and is classified as a type V DGK.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
DGKE protein structure - BS2281 shown in red.