AF1615

antibody from R&D Systems

Targeting: SEMA6A HT018, KIAA1368, SEMA, SEMA6A1, SEMAQ

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

AF1615

Provider

R&D Systems

Product name

Mouse Semaphorin 6A Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Detects mouse Semaphorin 6A in direct ELISAs and Western blots. In Western blots, approximately 25% cross-reactivity with recombinant human (rh) Semaphorin 6A is observed and less than 1% cross-reactivity with rhSemaphorin 3A, rhSemaphorin 3B, recombinant mouse (rm) Semaphorin 3C, rmSemaphorin 3F, and rmSemaphorin 7A is observed.

Reactivity

Mouse

Host

Goat

Conjugate

Unconjugated

Antigen sequence

O35464


Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

MicroRNA miR-27b rescues bone marrow-derived angiogenic cell function and accelerates wound healing in type 2 diabetes mellitus.

Wang JM, Tao J, Chen DD, Cai JJ, Irani K, Wang Q, Yuan H, Chen AF
Arteriosclerosis, thrombosis, and vascular biology 2014 Jan;34(1):99-109

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Semaphorin 6A regulates angiogenesis by modulating VEGF signaling.

Segarra M, Ohnuki H, Maric D, Salvucci O, Hou X, Kumar A, Li X, Tosato G
Blood 2012 Nov 8;120(19):4104-15

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Cis interaction between Semaphorin6A and Plexin-A4 modulates the repulsive response to Sema6A.

Haklai-Topper L, Mlechkovich G, Savariego D, Gokhman I, Yaron A
The EMBO journal 2010 Aug 4;29(15):2635-45