Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB2588 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2588, RRID:AB_1580446
- Product name
- SEMA6A polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of SEMA6A.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references From plasma membrane to cytoskeleton: a novel function for semaphorin 6A.
Comparative integromics on non-canonical WNT or planar cell polarity signaling molecules: transcriptional mechanism of PTK7 in colorectal cancer and that of SEMA6A in undifferentiated ES cells.
The class 6 semaphorin SEMA6A is induced by interferon-gamma and defines an activation status of langerhans cells observed in pathological situations.
Prislei S, Mozzetti S, Filippetti F, De Donato M, Raspaglio G, Cicchillitti L, Scambia G, Ferlini C
Molecular cancer therapeutics 2008 Jan;7(1):233-41
Molecular cancer therapeutics 2008 Jan;7(1):233-41
Comparative integromics on non-canonical WNT or planar cell polarity signaling molecules: transcriptional mechanism of PTK7 in colorectal cancer and that of SEMA6A in undifferentiated ES cells.
Katoh M, Katoh M
International journal of molecular medicine 2007 Sep;20(3):405-9
International journal of molecular medicine 2007 Sep;20(3):405-9
The class 6 semaphorin SEMA6A is induced by interferon-gamma and defines an activation status of langerhans cells observed in pathological situations.
Gautier G, de Saint-Vis B, Sénéchal B, Pin JJ, Bates EE, Caux C, Geissmann F, Garrone P
The American journal of pathology 2006 Feb;168(2):453-65
The American journal of pathology 2006 Feb;168(2):453-65
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of SEMA6A polyclonal antibody (Cat # PAB2588) pre-incubated with (right lane) and without (left lane) blocking peptide in mouse cerebellum tissue lysate. SEMA6A (arrow) was detected using the purified polyclonal antibody.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human brainreacted with SEMA6A polyclonal antibody (Cat # PAB2588), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)