19649-1-AP

antibody from Proteintech Group

Targeting: H1-2 H1.2, H1c, H1F2, H1s-1, HIST1H1C

Provider product page for 19649-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [18]
Comments [0]
Validations
Western blot [1]
Immunocytochemistry [1]
Immunoprecipitation [1]

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Product number: 19649-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#19649-1-AP, RRID:AB_10694432
Product name: Histone H1.2 antibody
Antibody type: Polyclonal
Description: Histone H1.2 antibody (Cat. #19649-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

H1-2 protein structure - 19649-1-AP shown in red.

Submitted references The Formation of Melanocyte Apoptotic Bodies in Vitiligo and the Relocation of Vitiligo Autoantigens under Oxidative Stress.

Tian J, Wang Y, Ding M, Zhang Y, Chi J, Wang T, Jiao B, Jian Z, Yi X, Huang Y, Liu L, Li K, Chen J, Wang G, Gao T, Li C, Li Q
Oxidative medicine and cellular longevity 2021;2021:7617839

Regulator of calcineurin 1 gene isoform 4 in pancreatic ductal adenocarcinoma regulates the progression of tumor cells.

Lao M, Zhang X, Ma T, Xu J, Yang H, Duan Y, Ying H, Zhang X, Guo C, Qiu J, Bai X, Liang T
Oncogene 2021 Apr;40(17):3136-3151

Rice protein stimulates endogenous antioxidant response attributed to methionine availability in growing rats.

Wang Z, Cai L, Li H, Liang M, Zhang Y, Wu Q, Yang L
Journal of food biochemistry 2020 May;44(5):e13180

Rice Protein Exerts Endogenous Antioxidant Capacity via Methionine Sulfoxide Reductase and the Nrf2 Antioxidant System Independent of Age.

Li H, Liang M, Wang Z, Zhang Y, Wu Q, Yang L
Journal of medicinal food 2020 Jun;23(6):565-574

Screening for reproductive biomarkers in Bactrian camel via iTRAQ analysis of proteomes.

Wang Q, Zhang Q, Gan Z, Li H, Yang Y, Zhang Y, Zhao X
Reproduction in domestic animals = Zuchthygiene 2020 Feb;55(2):189-199

RAD6B Plays a Critical Role in Neuronal DNA Damage Response to Resist Neurodegeneration.

Guo Z, Tian Y, Guo Y, Li B, Liu X, Xie K, Song Y, Wang D
Frontiers in cellular neuroscience 2019;13:392

Evidence for a novel mechanism of influenza A virus host adaptation modulated by PB2-627.

Liu X, Yang C, Sun X, Lin X, Zhao L, Chen H, Jin M
The FEBS journal 2019 Sep;286(17):3389-3400

Rice protein reduces DNA damage by activating the p53 pathway and stimulating endogenous antioxidant response in growing and adult rats.

Liang M, Li H, Wang Z, Cai L, Yang L
Journal of the science of food and agriculture 2019 Oct;99(13):6097-6107

Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.

Wang Z, Liang M, Li H, Cai L, Yang L
International journal of molecular sciences 2019 Dec 6;20(24)

l-Methionine activates Nrf2-ARE pathway to induce endogenous antioxidant activity for depressing ROS-derived oxidative stress in growing rats.

Wang Z, Liang M, Li H, Cai L, He H, Wu Q, Yang L
Journal of the science of food and agriculture 2019 Aug 15;99(10):4849-4862

New insights into meningitic Escherichia coli infection of brain microvascular endothelial cells from quantitative proteomics analysis.

Liu WT, Lv YJ, Yang RC, Fu JY, Liu L, Wang H, Cao Q, Tan C, Chen HC, Wang XR
Journal of neuroinflammation 2018 Oct 19;15(1):291

l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.

Liang M, Wang Z, Li H, Cai L, Pan J, He H, Wu Q, Tang Y, Ma J, Yang L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2018 May;115:315-328

Genome-wide distribution of linker histone H1.0 is independent of MeCP2.

Ito-Ishida A, Yamalanchili HK, Shao Y, Baker SA, Heckman LD, Lavery LA, Kim JY, Lombardi LM, Sun Y, Liu Z, Zoghbi HY
Nature neuroscience 2018 Jun;21(6):794-798

A20/TNFAIP3 Regulates the DNA Damage Response and Mediates Tumor Cell Resistance to DNA-Damaging Therapy.

Yang C, Zang W, Tang Z, Ji Y, Xu R, Yang Y, Luo A, Hu B, Zhang Z, Liu Z, Zheng X
Cancer research 2018 Feb 15;78(4):1069-1082

HIST1H1C Regulates Interferon-β and Inhibits Influenza Virus Replication by Interacting with IRF3.

Liu X, Yang C, Hu Y, Lei E, Lin X, Zhao L, Zou Z, Zhang A, Zhou H, Chen H, Qian P, Jin M
Frontiers in immunology 2017;8:350

C1QBP negatively regulates the activation of oncoprotein YBX1 in the renal cell carcinoma as revealed by interactomics analysis.

Wang Y, Yue D, Xiao M, Qi C, Chen Y, Sun D, Zhang N, Chen R
Journal of proteome research 2015 Feb 6;14(2):804-13

The linker histone h1.2 is an intermediate in the apoptotic response to cytokine deprivation in T-effectors.

Garg M, Perumalsamy LR, Shivashankar GV, Sarin A
International journal of cell biology 2014;2014:674753

PP2A inhibitors suppress migration and growth of PANC-1 pancreatic cancer cells through inhibition on the Wnt/β-catenin pathway by phosphorylation and degradation of β-catenin.

Wu MY, Xie X, Xu ZK, Xie L, Chen Z, Shou LM, Gong FR, Xie YF, Li W, Tao M
Oncology reports 2014 Aug;32(2):513-22

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: L02 cells were subjected to SDS PAGE followed by western blot with 19649-1-AP(HIST1H1C antibody) at dilution of 1:500
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunofluorescent analysis of Hela cells, using HIST1H1C antibody 19649-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: IP Result of anti-Histone H1.2 (IP:19649-1-AP, 3ug; Detection:19649-1-AP 1:500) with HeLa cells lysate 1600ug.
Sample type: cell line