DPABH-03844

antibody from Creative Diagnostics

Targeting: TNFAIP8 GG2-1, MDC-3.13, SCC-S2

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

DPABH-03844

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-03844, RRID:AB_2520493

Product name

Rabbit Anti-Human TNFAIP8 Polyclonal antibody

Antibody type

Polyclonal

Description

TNFAIP8(tumor necrosis factor, alpha-induced protein 8), also called SCC-S2/GG2-1/NDED, is associated with enhanced cell survival and inhibition of apoptosis. The induction of TNFAIP8 by TNF depends on the activation of NF¿¸B. TNFAIP8 suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. TNFAIP8 is expressed in adult spleen, lymph node, thymus, thyroid, bone marrow, and placenta, and in fetal liver, lung, and kidney at high levels, also expressed in various tumor tissues and all cancer cell lines tested.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50 uL