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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- NBP2-24877 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rabbit Polyclonal LOX Antibody
- Antibody type
- Polyclonal
- Description
- Unpurified.
- Reactivity
- Human, Mouse, Rat, Porcine, Sheep
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Type III collagen is a key regulator of the collagen fibrillar structure and biomechanics of articular cartilage and meniscus.
Cyclophilin B control of lysine post-translational modifications of skin type I collagen.
LOX-catalyzed collagen stabilization is a proximal cause for intrinsic resistance to chemotherapy.
Eliminating Regurgitation Reduces Fibrotic Remodeling of Functional Mitral Regurgitation Conditioned Valves.
Increased collagen cross-linking is a signature of dystrophin-deficient muscle.
Extracellular matrix remodeling in wound healing of critical size defects in the mitral valve leaflet.
Regurgitation Hemodynamics Alone Cause Mitral Valve Remodeling Characteristic of Clinical Disease States In Vitro.
Cellular and Extracellular Matrix Basis for Heterogeneity in Mitral Annular Contraction.
Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival.
Alfacalcidol enhances collagen quality in ovariectomized rat bones.
Development of collagen fibres and lysyl oxidase expression in the presumptive dermis of chick limb bud.
A novel proteolytic processing of prolysyl oxidase.
Organ culture as a tool to identify early mechanisms of serotonergic valve disease.
Arterial stiffening with ageing is associated with transforming growth factor-β1-related changes in adventitial collagen: reversal by aerobic exercise.
Design and validation of a novel splashing bioreactor system for use in mitral valve organ culture.
Perinatal changes in mitral and aortic valve structure and composition.
Reciprocal regulation of LOX and LOXL2 expression during cell adhesion and terminal differentiation in epidermal keratinocytes.
Occlusal hypofunction induces atrophic changes in rat gingiva.
Lysyl oxidase binds transforming growth factor-beta and regulates its signaling via amine oxidase activity.
Wang C, Brisson BK, Terajima M, Li Q, Hoxha K, Han B, Goldberg AM, Sherry Liu X, Marcolongo MS, Enomoto-Iwamoto M, Yamauchi M, Volk SW, Han L
Matrix biology : journal of the International Society for Matrix Biology 2020 Jan;85-86:47-67
Matrix biology : journal of the International Society for Matrix Biology 2020 Jan;85-86:47-67
Cyclophilin B control of lysine post-translational modifications of skin type I collagen.
Terajima M, Taga Y, Cabral WA, Liu Y, Nagasawa M, Sumida N, Kayashima Y, Chandrasekaran P, Han L, Maeda N, Perdivara I, Hattori S, Marini JC, Yamauchi M
PLoS genetics 2019 Jun;15(6):e1008196
PLoS genetics 2019 Jun;15(6):e1008196
LOX-catalyzed collagen stabilization is a proximal cause for intrinsic resistance to chemotherapy.
Rossow L, Veitl S, Vorlová S, Wax JK, Kuhn AE, Maltzahn V, Upcin B, Karl F, Hoffmann H, Gätzner S, Kallius M, Nandigama R, Scheld D, Irmak S, Herterich S, Zernecke A, Ergün S, Henke E
Oncogene 2018 Sep;37(36):4921-4940
Oncogene 2018 Sep;37(36):4921-4940
Eliminating Regurgitation Reduces Fibrotic Remodeling of Functional Mitral Regurgitation Conditioned Valves.
Connell PS, Vekilov DP, Diaz CM, Kim SE, Grande-Allen KJ
Annals of biomedical engineering 2018 May;46(5):670-683
Annals of biomedical engineering 2018 May;46(5):670-683
Increased collagen cross-linking is a signature of dystrophin-deficient muscle.
Smith LR, Hammers DW, Sweeney HL, Barton ER
Muscle & nerve 2016 Jun;54(1):71-8
Muscle & nerve 2016 Jun;54(1):71-8
Extracellular matrix remodeling in wound healing of critical size defects in the mitral valve leaflet.
Stephens EH, Nguyen TC, Blazejewski JG, Vekilov DP, Connell JP, Itoh A, Ingels NB Jr, Miller DC, Grande-Allen KJ
Heart and vessels 2016 Jul;31(7):1186-95
Heart and vessels 2016 Jul;31(7):1186-95
Regurgitation Hemodynamics Alone Cause Mitral Valve Remodeling Characteristic of Clinical Disease States In Vitro.
Connell PS, Azimuddin AF, Kim SE, Ramirez F, Jackson MS, Little SH, Grande-Allen KJ
Annals of biomedical engineering 2016 Apr;44(4):954-67
Annals of biomedical engineering 2016 Apr;44(4):954-67
Cellular and Extracellular Matrix Basis for Heterogeneity in Mitral Annular Contraction.
Stephens EH, Fahrenholtz MM, Connell PS, Timek TA, Daughters GT, Kuo JJ, Patton AM, Ingels NB Jr, Miller DC, Grande-Allen KJ
Cardiovascular engineering and technology 2015 Jun;6(2):151-9
Cardiovascular engineering and technology 2015 Jun;6(2):151-9
Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival.
Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R
Cancer cell 2014 Jun 16;25(6):719-34
Cancer cell 2014 Jun 16;25(6):719-34
Alfacalcidol enhances collagen quality in ovariectomized rat bones.
Nagaoka H, Terajima M, Yamada S, Azuma Y, Chida T, Yamauchi M
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2014 Aug;32(8):1030-6
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2014 Aug;32(8):1030-6
Development of collagen fibres and lysyl oxidase expression in the presumptive dermis of chick limb bud.
Yamazaki Y, Mikami Y, Yuguchi M, Namba Y, Isokawa K
Anatomia, histologia, embryologia 2012 Feb;41(1):68-74
Anatomia, histologia, embryologia 2012 Feb;41(1):68-74
A novel proteolytic processing of prolysyl oxidase.
Atsawasuwan P, Mochida Y, Katafuchi M, Tokutomi K, Mocanu V, Parker CE, Yamauchi M
Connective tissue research 2011;52(6):479-86
Connective tissue research 2011;52(6):479-86
Organ culture as a tool to identify early mechanisms of serotonergic valve disease.
Barzilla JE, Acevedo FE, Grande-Allen KJ
The Journal of heart valve disease 2010 Sep;19(5):626-35
The Journal of heart valve disease 2010 Sep;19(5):626-35
Arterial stiffening with ageing is associated with transforming growth factor-β1-related changes in adventitial collagen: reversal by aerobic exercise.
Fleenor BS, Marshall KD, Durrant JR, Lesniewski LA, Seals DR
The Journal of physiology 2010 Oct 15;588(Pt 20):3971-82
The Journal of physiology 2010 Oct 15;588(Pt 20):3971-82
Design and validation of a novel splashing bioreactor system for use in mitral valve organ culture.
Barzilla JE, McKenney AS, Cowan AE, Durst CA, Grande-Allen KJ
Annals of biomedical engineering 2010 Nov;38(11):3280-94
Annals of biomedical engineering 2010 Nov;38(11):3280-94
Perinatal changes in mitral and aortic valve structure and composition.
Stephens EH, Post AD, Laucirica DR, Grande-Allen KJ
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2010 Nov-Dec;13(6):447-58
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2010 Nov-Dec;13(6):447-58
Reciprocal regulation of LOX and LOXL2 expression during cell adhesion and terminal differentiation in epidermal keratinocytes.
Fujimoto E, Tajima S
Journal of dermatological science 2009 Aug;55(2):91-8
Journal of dermatological science 2009 Aug;55(2):91-8
Occlusal hypofunction induces atrophic changes in rat gingiva.
Ishida Y, Kanno Z, Soma K
The Angle orthodontist 2008 Nov;78(6):1015-22
The Angle orthodontist 2008 Nov;78(6):1015-22
Lysyl oxidase binds transforming growth factor-beta and regulates its signaling via amine oxidase activity.
Atsawasuwan P, Mochida Y, Katafuchi M, Kaku M, Fong KS, Csiszar K, Yamauchi M
The Journal of biological chemistry 2008 Dec 5;283(49):34229-40
The Journal of biological chemistry 2008 Dec 5;283(49):34229-40
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: LOX Antibody [NBP2-24877] - Analysis of LOX in A) human skin and B) mouse ear skin lysate using NBP2-24877 at 1:500. Goat anti-rabbit IgG HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: LOX Antibody [NBP2-24877] - Analysis of mouse ear lysate when LOX antibody (NBP2-24877) was used at 1:1000. The band shown is the expected inactive 50 kD proenzyme.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: LOX Antibody [NBP2-24877] - Analysis of LOX in formalin-fixed, paraffin-embedded mouse skin using an isotype control (top) and NBP2-24877 (bottom) at 1:100.
