Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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Comment
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- Product number
- PAB12403 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12403, RRID:AB_10552233
- Product name
- LOX polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of LOX.
- Storage
- Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Lysyl oxidase secreted by tumour endothelial cells promotes angiogenesis and metastasis.
Anthracycline inhibits recruitment of hypoxia-inducible transcription factors and suppresses tumor cell migration and cardiac angiogenic response in the host.
Lysyl oxidase is essential for hypoxia-induced metastasis.
The Pro-regions of lysyl oxidase and lysyl oxidase-like 1 are required for deposition onto elastic fibers.
Post-translational glycosylation and proteolytic processing of a lysyl oxidase precursor.
Osawa T, Ohga N, Akiyama K, Hida Y, Kitayama K, Kawamoto T, Yamamoto K, Maishi N, Kondoh M, Onodera Y, Fujie M, Shinohara N, Nonomura K, Shindoh M, Hida K
British journal of cancer 2013 Oct 15;109(8):2237-47
British journal of cancer 2013 Oct 15;109(8):2237-47
Anthracycline inhibits recruitment of hypoxia-inducible transcription factors and suppresses tumor cell migration and cardiac angiogenic response in the host.
Tanaka T, Yamaguchi J, Shoji K, Nangaku M
The Journal of biological chemistry 2012 Oct 12;287(42):34866-82
The Journal of biological chemistry 2012 Oct 12;287(42):34866-82
Lysyl oxidase is essential for hypoxia-induced metastasis.
Erler JT, Bennewith KL, Nicolau M, Dornhöfer N, Kong C, Le QT, Chi JT, Jeffrey SS, Giaccia AJ
Nature 2006 Apr 27;440(7088):1222-6
Nature 2006 Apr 27;440(7088):1222-6
The Pro-regions of lysyl oxidase and lysyl oxidase-like 1 are required for deposition onto elastic fibers.
Thomassin L, Werneck CC, Broekelmann TJ, Gleyzal C, Hornstra IK, Mecham RP, Sommer P
The Journal of biological chemistry 2005 Dec 30;280(52):42848-55
The Journal of biological chemistry 2005 Dec 30;280(52):42848-55
Post-translational glycosylation and proteolytic processing of a lysyl oxidase precursor.
Trackman PC, Bedell-Hogan D, Tang J, Kagan HM
The Journal of biological chemistry 1992 Apr 25;267(12):8666-71
The Journal of biological chemistry 1992 Apr 25;267(12):8666-71
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of LOX in mouse kidney lysate using LOX polyclonal antibody (Cat # PAB12403) (1 : 1,000).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Staining of LOX on placental trophoblasts using LOX polyclonal antibody (Cat # PAB12403) at 10 ug/mL .
- Validation comment
- Immunohistochemistry