Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- H00051191-A01 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00051191-A01, RRID:AB_2117835
- Product name
- Mouse Polyclonal HERC5 Antibody
- Antibody type
- Polyclonal
- Description
- Unpurified. HERC5 - hect domain and RLD 5
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.05 ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references 90K Glycoprotein Promotes Degradation of Mutant β-Catenin Lacking the ISGylation or Phosphorylation Sites in the N-terminus.
Covalent ISG15 conjugation positively regulates the ubiquitin E3 ligase activity of parkin.
Interferon-induced HERC5 is evolving under positive selection and inhibits HIV-1 particle production by a novel mechanism targeting Rev/RRE-dependent RNA nuclear export.
Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of Gag.
Fullerene derivatives induce premature senescence: a new toxicity paradigm or novel biomedical applications.
Park SY, Yoon S, Kim H, Kim KK
Neoplasia (New York, N.Y.) 2016 Oct;18(10):618-625
Neoplasia (New York, N.Y.) 2016 Oct;18(10):618-625
Covalent ISG15 conjugation positively regulates the ubiquitin E3 ligase activity of parkin.
Im E, Yoo L, Hyun M, Shin WH, Chung KC
Open biology 2016 Aug;6(8)
Open biology 2016 Aug;6(8)
Interferon-induced HERC5 is evolving under positive selection and inhibits HIV-1 particle production by a novel mechanism targeting Rev/RRE-dependent RNA nuclear export.
Woods MW, Tong JG, Tom SK, Szabo PA, Cavanagh PC, Dikeakos JD, Haeryfar SM, Barr SD
Retrovirology 2014 Apr 3;11:27
Retrovirology 2014 Apr 3;11:27
Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of Gag.
Woods MW, Kelly JN, Hattlmann CJ, Tong JG, Xu LS, Coleman MD, Quest GR, Smiley JR, Barr SD
Retrovirology 2011 Nov 17;8:95
Retrovirology 2011 Nov 17;8:95
Fullerene derivatives induce premature senescence: a new toxicity paradigm or novel biomedical applications.
Gao J, Wang HL, Shreve A, Iyer R
Toxicology and applied pharmacology 2010 Apr 15;244(2):130-43
Toxicology and applied pharmacology 2010 Apr 15;244(2):130-43
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: HERC5 Antibody [H00051191-A01] - Detection against Immunogen (38.21 KDa) .