Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 10287-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10287-2-AP, RRID:AB_2169424
- Product name
- CYPC antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CYPC antibody (Cat. #10287-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Extracellular cyclophilins A and C induce dysfunction of pancreatic microendothelial cells.
Furanoditerpenes from Spongia (Spongia) tubulifera Display Mitochondrial-Mediated Neuroprotective Effects by Targeting Cyclophilin D.
Pharmacological Targeting of the ER-Resident Chaperones GRP94 or Cyclophilin B Induces Secretion of IL-22 Binding Protein Isoform-1 (IL-22BPi1).
Cyclophilin C Participates in the US2-Mediated Degradation of Major Histocompatibility Complex Class I Molecules.
Depletion of cyclophilins B and C leads to dysregulation of endoplasmic reticulum redox homeostasis.
The isomerase active site of cyclophilin A is critical for hepatitis C virus replication.
Alvariño R, Alfonso A, Pérez-Fuentes N, González-Jartín JM, Gegunde S, Vieytes MR, Botana LM
Frontiers in physiology 2022;13:980232
Frontiers in physiology 2022;13:980232
Furanoditerpenes from Spongia (Spongia) tubulifera Display Mitochondrial-Mediated Neuroprotective Effects by Targeting Cyclophilin D.
Alvariño R, Alfonso A, Pech-Puch D, Gegunde S, Rodríguez J, Vieytes MR, Jiménez C, Botana LM
ACS chemical neuroscience 2022 Aug 17;13(16):2449-2463
ACS chemical neuroscience 2022 Aug 17;13(16):2449-2463
Pharmacological Targeting of the ER-Resident Chaperones GRP94 or Cyclophilin B Induces Secretion of IL-22 Binding Protein Isoform-1 (IL-22BPi1).
Gómez-Fernández P, Urtasun A, Astobiza I, Mena J, Alloza I, Vandenbroeck K
International journal of molecular sciences 2019 May 17;20(10)
International journal of molecular sciences 2019 May 17;20(10)
Cyclophilin C Participates in the US2-Mediated Degradation of Major Histocompatibility Complex Class I Molecules.
Chapman DC, Stocki P, Williams DB
PloS one 2015;10(12):e0145458
PloS one 2015;10(12):e0145458
Depletion of cyclophilins B and C leads to dysregulation of endoplasmic reticulum redox homeostasis.
Stocki P, Chapman DC, Beach LA, Williams DB
The Journal of biological chemistry 2014 Aug 15;289(33):23086-23096
The Journal of biological chemistry 2014 Aug 15;289(33):23086-23096
The isomerase active site of cyclophilin A is critical for hepatitis C virus replication.
Chatterji U, Bobardt M, Selvarajah S, Yang F, Tang H, Sakamoto N, Vuagniaux G, Parkinson T, Gallay P
The Journal of biological chemistry 2009 Jun 19;284(25):16998-17005
The Journal of biological chemistry 2009 Jun 19;284(25):16998-17005
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 10287-2-AP(CYPC antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CYPC antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CYPC. This antibody recognizes human,mouse,rat antigen. The CYPC antibody has been validated for the following applications: ELISA, WB, IHC analysis.