BS8331

antibody from Bioworld Technology, Inc
Targeting: MMRN1 ECM, EMILIN4, GPIa*, MMRN
Provider product page for BS8331
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8331 - Provider product page
Provider
Bioworld Technology, Inc
Product name
MMRN1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human MMRN1.
Description
Multimerin-1, also known as MMRN1, EMILIN-4 or ECM (endothelial cell multimerin), is a 1,228 amino acid secreted protein that contains one C1q domain, one EMI domain and one EGF-like domain. Synthesized in megakaryocytes and endothelial cells and present in liver, lung and placenta, Multimerin-1 exists as a multimeric structure composed of varying disulfide-linked multimers and functions as a carrier protein for platelet factors (specifically platelet factor V), playing a role in the stabilization and storage of factor V in platelets. In addition, Multimerin-1 acts as a ligand for select Integrins and may participate in extracellular matrix adhesion. Defects in the gene encoding Multimerin-1 that lead to Multimerin-1 deficiency are associated with autosomal dominant bleeding disorders due to platelet factor malfunction. Multiple isoforms of Multimerin-1 exist due to alternative splicing events.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MMRN1 protein structure - BS8331 shown in red.