Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- BS6474 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- CACNG2 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human CACNG2.
- Description
- Excitable cells in response to membrane depolarization are involved in a variety of Ca++-dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression. Calcium channels are highly diverse, multimeric complexes composed of an alpha1 subunit, an intracellular beta subunit, a disulfide linked alpha2/delta subunit and a transmembrane gamma subunit. L-type Ca++ currents initiate muscle contraction, endocrine secretion and gene transcription, and are regulated through second-messenger activated protein phosphorylation pathways. L-type calcium channels may form macromolecular signaling complexes with G protein-coupled receptors, thereby enhancing the selectivity of regulating specific targets. L-type calcium channels in the brain specifically express the gamma2 subunit along with gamma3 and gamma4 subunits. The gamma2 subunit (also known as stargazin) is abundant in synaptic plasma membranes where it regulates synaptic targeting of AMP receptors in granule cells.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
No comments: Submit comment
No validations: Submit validation data