DPABH-01285

antibody from Creative Diagnostics

Targeting: MLH3

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

DPABH-01285

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-01285, RRID:AB_2519727

Product name

Rabbit Anti-Human MLH3 Polyclonal antibody

Antibody type

Polyclonal

Description

This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50 uL