BS64038

antibody from Bioworld Technology, Inc
Targeting: EIF2S2 EIF2, EIF2beta, PPP1R67
Provider product page for BS64038

Antibody data

Product number
BS64038 - Provider product page
Provider
Bioworld Technology, Inc
Product name
EIF2S2 (phospho S67) polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human EIF2S2 around the phosphorylation site of ser67.
Description
The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex eIF2 exists as a heterotrimeric complex of eIF2Ï«, eIF2? and eIF2ÎÛ. eIF2 functions in the early stages of protein synthesis, by forming a ternary complex with GTP and tRNA. This complex binds to the 40S ribosomal subunit, followed by mRNA binding to 40S to form the 43S preinitiation complex, the release of eIF2 from 40S, and the hydrolysis of GTP. Phosphorylation of eIF2a correlates with inhibition of translation initiation .
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
EIF2S2 protein structure - BS64038 shown in red.