BS8554

antibody from Bioworld Technology, Inc
Targeting: ASIP AGTIL, ASP
Provider product page for BS8554
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8554 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ASIP polyclonal antibody
Antibody type
Polyclonal
Antigen
Agouti-signaling protein; ASP; Agouti switch protein; ASIP; AGTI, AGTIL, ASP
Description
In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ASIP protein structure - BS8554 shown in red.