orb536334

antibody from Biorbyt

Targeting: ASIP AGTIL, ASP

Immunocytochemistry (Data presented on provider website)

Antibody Data

Product number

orb536334

Provider

Biorbyt

Product name

ASIP antibody

Antibody type

Polyclonal

Description

In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.

Reactivity

Human

Conjugate

Unconjugated

Isotype

IgG

Vial size

50 ul

Storage

Store at -20°C. Avoid freeze / thaw cycles.