FNab05562

antibody from FineTest Biotech
Targeting: NAT10 FLJ10774, FLJ12179, hALP, KIAA1709, Kre33, NET43
Provider product page for FNab05562
Western blot
ELISA
Immunocytochemistry
Immunoprecipitation

Antibody data

Product number
FNab05562 - Provider product page
Provider
FineTest Biotech
Product name
NAT10 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs(PubMed:25653167). Catalyzes the formation of N(4)-acetylcytidine(ac4C) at positions 1337 and 1842 in 18S rRNA(By similarity). Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis(PubMed:25653167). Catalyzes the formation of ac4C in serine and leucine tRNAs(By similarity). Requires the tRNA-binding adapter protein THUMBD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation(PubMed:25653167). Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division(PubMed:14592445, PubMed:17631499, PubMed:18082603, PubMed:19303003).
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
N-acetyltransferase 10(GCN5-related
)
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
NAT10 protein structure - FNab05562 shown in red.