FNab05562
antibody from FineTest Biotech
Targeting: NAT10
FLJ10774, FLJ12179, hALP, KIAA1709, Kre33, NET43
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations [0]
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- Product number
- FNab05562 - Provider product page
- Provider
- FineTest Biotech
- Product name
- NAT10 antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant protein fragment
- Description
- RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs(PubMed:25653167). Catalyzes the formation of N(4)-acetylcytidine(ac4C) at positions 1337 and 1842 in 18S rRNA(By similarity). Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis(PubMed:25653167). Catalyzes the formation of ac4C in serine and leucine tRNAs(By similarity). Requires the tRNA-binding adapter protein THUMBD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation(PubMed:25653167). Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division(PubMed:14592445, PubMed:17631499, PubMed:18082603, PubMed:19303003).
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Antigen sequence
N-acetyltransferase 10(GCN5-related
)- Epitope
- IgG
- Isotype
- IgG
- Vial size
- 100¦Ìg
- Concentration
- Immunogen affinity purified
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
- Handling
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
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