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LearnPAB13236
antibody from Abnova Corporation
Targeting: TMED10
p23, P24(DELTA), p24d1, p24delta1, TMP21
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB13236 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB13236, RRID:AB_10676149
- Product name
- TMED10 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of TMED10.
- Storage
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity.
Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2.
Tmp21 and p24A, two type I proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking.
Chen F, Hasegawa H, Schmitt-Ulms G, Kawarai T, Bohm C, Katayama T, Gu Y, Sanjo N, Glista M, Rogaeva E, Wakutani Y, Pardossi-Piquard R, Ruan X, Tandon A, Checler F, Marambaud P, Hansen K, Westaway D, St George-Hyslop P, Fraser P
Nature 2006 Apr 27;440(7088):1208-12
Nature 2006 Apr 27;440(7088):1208-12
Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2.
Periz G, Fortini ME
Journal of neuroscience research 2004 Aug 1;77(3):309-22
Journal of neuroscience research 2004 Aug 1;77(3):309-22
Tmp21 and p24A, two type I proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking.
Blum R, Feick P, Puype M, Vandekerckhove J, Klengel R, Nastainczyk W, Schulz I
The Journal of biological chemistry 1996 Jul 19;271(29):17183-9
The Journal of biological chemistry 1996 Jul 19;271(29):17183-9
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of TMED10 in mouse brain tissue lysate with TMED10 polyclonal antibody (Cat # PAB13236) at (A) 0.5, (B) 1 and (C) 2 ug/mL .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemistry of TMED10 in human brain tissue with TMED10 polyclonal antibody (Cat # PAB13236) at 5 ug/mL .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
