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LearnABIN500992
antibody from antibodies-online
Targeting: TMED10
p23, P24(DELTA), p24d1, p24delta1, TMP21
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN500992 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Transmembrane Emp24-Like Trafficking Protein 10 (Yeast) (TMED10) (Center) antibody
- Antibody type
- Polyclonal
- Antigen
- TMP21 antibody was raised against a 18 amino acid peptide from near the center of humanTMP21.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing. Shelf life: one year from despatch.
Submitted references TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity.
Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2.
The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease.
Tmp21 and p24A, two type I proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking.
Chen F, Hasegawa H, Schmitt-Ulms G, Kawarai T, Bohm C, Katayama T, Gu Y, Sanjo N, Glista M, Rogaeva E, Wakutani Y, Pardossi-Piquard R, Ruan X, Tandon A, Checler F, Marambaud P, Hansen K, Westaway D, St George-Hyslop P, Fraser P
Nature 2006 Apr 27;440(7088):1208-12
Nature 2006 Apr 27;440(7088):1208-12
Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2.
Periz G, Fortini ME
Journal of neuroscience research 2004 Aug 1;77(3):309-22
Journal of neuroscience research 2004 Aug 1;77(3):309-22
The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease.
Selkoe DJ
Trends in cell biology 1998 Nov;8(11):447-53
Trends in cell biology 1998 Nov;8(11):447-53
Tmp21 and p24A, two type I proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking.
Blum R, Feick P, Puype M, Vandekerckhove J, Klengel R, Nastainczyk W, Schulz I
The Journal of biological chemistry 1996 Jul 19;271(29):17183-9
The Journal of biological chemistry 1996 Jul 19;271(29):17183-9
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of TMP21 in mouse brain tissue lysate with AP30920PU-N at (A) 0.5, (B) 1 and (C) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of TMP21 in human brain tissue with AP30920PU-N at 5 ?g/ml.
