FNab08321

antibody from FineTest Biotech

Targeting: STIM1 D11S4896E, GOK

Western blot

ELISA

Immunohistochemistry

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Validation data

Product number: FNab08321 - Provider product page
Provider: FineTest Biotech
Product name: STIM1 antibody
Antibody type: Monoclonal
Antigen: Recombinant protein fragment
Description: Plays a role in mediating store-operated Ca(2+) entry(SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores(By similarity). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+)(CRAC) channel subunit ORAI1(PubMed:16208375). Involved in enamel formation(By similarity). Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch(By similarity).
Reactivity: Human, Mouse, Rat
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: stromal interaction molecule 1
Epitope: IgG2a
Isotype: IgG
Antibody clone number: 4G6
Vial size: 100¦Ìg
Concentration: Protein A+G purification
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

STIM1 protein structure - FNab08321 shown in red.