BS3140

antibody from Bioworld Technology, Inc

Targeting: ACSL6 ACS2, FACL6, KIAA0837, LACS2, LACS5

Immunohistochemistry

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Validation data

Product number: BS3140 - Provider product page
Provider: Bioworld Technology, Inc
Proper citation: Bioworld Technology Cat#BS3140, RRID:AB_1663150
Product name: ACSL6 (D531) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic peptide, corresponding to amino acids 500-550 of Human ACSL6.
Description: Acyl-CoA synthetases, also known as long-chain fatty-acid CoA synthases (FACL) or Palmitoyl-CoA ligases, include ACSL1-6, which are all single-pass membrane proteins localizing to the mitochondrion, microsome or peroxisome.ACSL proteins are important for synthesis of cellular lipids and for ÉÇ-oxidation degradation. Specifically, ACSL proteins catalyze the activation of long-chain fatty acids to acyl-CoAs, which can be metabolized to form CO2, triacylglycerol (TAG), phospholipids (PL) and cholesteryl esters (CE). ACSL6 has been shown to be an ETV6 fusion partner gene in a recurrent t(5;12) (q31;p13) translocation in a patient with refractory anemia with excess blasts (RAEB) with basophilia, a patient with acute myelogenous leukemia (AML) with eosinophilia, and a patient with acute eosinophilic leukemia (AEL).
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

ACSL6 protein structure - BS3140 shown in red.