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- Antibody Data
- Antigen structure
- References [17]
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- Validations
- Immunohistochemistry [2]
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- Product number
- 11594-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ACP5 antibody
- Antibody type
- Polyclonal
- Description
- ACP5 antibody (Cat. #11594-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IHC,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Decrease of lysyl hydroxylase 2 activity causes abnormal collagen molecular phenotypes, defective mineralization and compromised mechanical properties of bone.
Prognostic Significance of ACP5 in Human Gastric Cancer.
Single-Cell RNA Sequencing Reveals the Migration of Osteoclasts in Giant Cell Tumor of Bone.
Hexokinase 2-mediated glycolysis promotes receptor activator of NF-κB ligand expression in Porphyromonas gingivalis lipopolysaccharide-treated osteoblasts.
The function of the calcium channel Orai1 in osteoclast development.
4-Hexylresorcinol inhibits osteoclastogenesis by suppressing the NF-κB signaling pathway and reverses bone loss in ovariectomized mice.
Pristimerin Suppresses RANKL-Induced Osteoclastogenesis and Ameliorates Ovariectomy-Induced Bone Loss.
Cytisine attenuates bone loss of ovariectomy mouse by preventing RANKL-induced osteoclastogenesis.
Vinpocetine inhibits RANKL-induced osteoclastogenesis and attenuates ovariectomy-induced bone loss.
Tartrate-Resistant Acid Phosphatase 5/ACP5 Interacts with p53 to Control the Expression of SMAD3 in Lung Adenocarcinoma.
Fluid Shear Stress Suppresses Osteoclast Differentiation in RAW264.7 Cells through Extracellular Signal-Regulated Kinase 5 (ERK5) Signaling Pathway.
Tetrandrine Prevents Bone Loss in Ovariectomized Mice by Inhibiting RANKL-Induced Osteoclastogenesis.
miR-142-5p promotes the osteoclast differentiation of bone marrow-derived macrophages via PTEN/PI3K/AKT/FoxO1 pathway.
Hesperetin suppresses RANKL-induced osteoclastogenesis and ameliorates lipopolysaccharide-induced bone loss.
Effects of Taxifolin on Osteoclastogenesis in vitro and in vivo.
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Secreted Klotho Attenuates Inflammation-Associated Aortic Valve Fibrosis in Senescence-Accelerated Mice P1.
Saito T, Terajima M, Taga Y, Hayashi F, Oshima S, Kasamatsu A, Okubo Y, Ito C, Toshimori K, Sunohara M, Tanzawa H, Uzawa K, Yamauchi M
Bone 2022 Jan;154:116242
Bone 2022 Jan;154:116242
Prognostic Significance of ACP5 in Human Gastric Cancer.
An T, Liang Q, Hao T, Deng L, Lu X, Wang Y, Cheng L, Wu W, Zhang C
Digestive diseases (Basel, Switzerland) 2021;39(4):310-317
Digestive diseases (Basel, Switzerland) 2021;39(4):310-317
Single-Cell RNA Sequencing Reveals the Migration of Osteoclasts in Giant Cell Tumor of Bone.
Feng W, He M, Jiang X, Liu H, Xie T, Qin Z, Huang Q, Liao S, Lin C, He J, Xu J, Ma J, Liu Y, Wei Q
Frontiers in oncology 2021;11:715552
Frontiers in oncology 2021;11:715552
Hexokinase 2-mediated glycolysis promotes receptor activator of NF-κB ligand expression in Porphyromonas gingivalis lipopolysaccharide-treated osteoblasts.
Yu Y, Jiang L, Li J, Lei L, Li H
Journal of periodontology 2021 Sep 29;
Journal of periodontology 2021 Sep 29;
The function of the calcium channel Orai1 in osteoclast development.
Robinson LJ, Soboloff J, Tourkova IL, Larrouture QC, Witt MR, Gross S, Hooper R, Samakai E, Worley PF, Barnett JB, Blair HC
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jun;35(6):e21653
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jun;35(6):e21653
4-Hexylresorcinol inhibits osteoclastogenesis by suppressing the NF-κB signaling pathway and reverses bone loss in ovariectomized mice.
Yi W, Liu T, Gao X, Xie Y, Liu M
Experimental and therapeutic medicine 2021 Apr;21(4):354
Experimental and therapeutic medicine 2021 Apr;21(4):354
Pristimerin Suppresses RANKL-Induced Osteoclastogenesis and Ameliorates Ovariectomy-Induced Bone Loss.
Qi D, Liu H, Sun X, Luo D, Zhu M, Tao T, Gao C, Zhou C, Zhou W, Xiao J
Frontiers in pharmacology 2020;11:621110
Frontiers in pharmacology 2020;11:621110
Cytisine attenuates bone loss of ovariectomy mouse by preventing RANKL-induced osteoclastogenesis.
Qian Z, Zhong Z, Ni S, Li D, Zhang F, Zhou Y, Kang Z, Qian J, Yu B
Journal of cellular and molecular medicine 2020 Sep;24(17):10112-10127
Journal of cellular and molecular medicine 2020 Sep;24(17):10112-10127
Vinpocetine inhibits RANKL-induced osteoclastogenesis and attenuates ovariectomy-induced bone loss.
Zhu M, Liu H, Sun K, Liu J, Mou Y, Qi D, Zhou C, Abudunaibi M, Tasiken B, Li J, Cheng H, Huang H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109769
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109769
Tartrate-Resistant Acid Phosphatase 5/ACP5 Interacts with p53 to Control the Expression of SMAD3 in Lung Adenocarcinoma.
Hu Y, Yu J, Wang Q, Zhang L, Chen X, Cao Y, Zhao J, Xu Y, Jiang D, Wang Y, Xiong W
Molecular therapy oncolytics 2020 Mar 27;16:272-288
Molecular therapy oncolytics 2020 Mar 27;16:272-288
Fluid Shear Stress Suppresses Osteoclast Differentiation in RAW264.7 Cells through Extracellular Signal-Regulated Kinase 5 (ERK5) Signaling Pathway.
Ma C, Geng B, Zhang X, Li R, Yang X, Xia Y
Medical science monitor : international medical journal of experimental and clinical research 2020 Jan 8;26:e918370
Medical science monitor : international medical journal of experimental and clinical research 2020 Jan 8;26:e918370
Tetrandrine Prevents Bone Loss in Ovariectomized Mice by Inhibiting RANKL-Induced Osteoclastogenesis.
Zhong Z, Qian Z, Zhang X, Chen F, Ni S, Kang Z, Zhang F, Li D, Yu B
Frontiers in pharmacology 2019;10:1530
Frontiers in pharmacology 2019;10:1530
miR-142-5p promotes the osteoclast differentiation of bone marrow-derived macrophages via PTEN/PI3K/AKT/FoxO1 pathway.
Lou Z, Peng Z, Wang B, Li X, Li X, Zhang X
Journal of bone and mineral metabolism 2019 Sep;37(5):815-824
Journal of bone and mineral metabolism 2019 Sep;37(5):815-824
Hesperetin suppresses RANKL-induced osteoclastogenesis and ameliorates lipopolysaccharide-induced bone loss.
Liu H, Dong Y, Gao Y, Zhao L, Cai C, Qi D, Zhu M, Zhao L, Liu C, Guo F, Xiao J, Huang H
Journal of cellular physiology 2019 Jul;234(7):11009-11022
Journal of cellular physiology 2019 Jul;234(7):11009-11022
Effects of Taxifolin on Osteoclastogenesis in vitro and in vivo.
Cai C, Liu C, Zhao L, Liu H, Li W, Guan H, Zhao L, Xiao J
Frontiers in pharmacology 2018;9:1286
Frontiers in pharmacology 2018;9:1286
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Zhang X, Li X, Fang J, Hou X, Fang H, Guo F, Li F, Chen A, Huang S
Journal of cellular biochemistry 2018 Nov;119(11):8981-8995
Journal of cellular biochemistry 2018 Nov;119(11):8981-8995
Secreted Klotho Attenuates Inflammation-Associated Aortic Valve Fibrosis in Senescence-Accelerated Mice P1.
Chen J, Fan J, Wang S, Sun Z
Hypertension (Dallas, Tex. : 1979) 2018 May;71(5):877-885
Hypertension (Dallas, Tex. : 1979) 2018 May;71(5):877-885
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 11594-1-AP(ACP5 antibody) at dilution of 1:25 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ACP5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ACP5. This antibody recognizes human,mouse,rat antigen. The ACP5 antibody has been validated for the following applications: ELISA, IHC analysis.
