Tissue expression
Cell line expression
Protein structure
GDF6
Growth differentiation factor 6BMP13, KFS, KFS1, SGM1
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene are associated with Klippel-Feil syndrome, microphthalmia, and Leber congenital amaurosis. [provided by RefSeq, Sep 2016]
Top validated antibodies |
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antibodies-online | ABIN950666 | 3 references | Polyclonal |
WB
IHC
FC
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Aviva Systems Biology | OAAB04538 | Polyclonal |
WB
EL
IHC
FC |
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Abgent | AP11672a | Polyclonal |
WB
IHC
FC
|
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Acris Antibodies GmbH | AP51812PU-N | Polyclonal |
WB
IHC
FC
|
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OriGene | AP51812PU-N | Polyclonal |
WB
IHC
FC
|
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