MAB1108

antibody from R&D Systems

Targeting: KLK5 KLK-L2, SCTE

Western blot (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Antibody Data

Product number

MAB1108

Provider

R&D Systems

Product name

Human Kallikrein 5 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects human Kallikrein 5 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) Kallikrein 3, rhKallikrein 4, rhKallikrein 8, or rhKallikrein 11 is observed.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Antigen sequence

Q9Y337


Isotype

IgG

Antibody clone number

193318

Vial size

500 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Proteolytic activation cascade of the Netherton syndrome-defective protein, LEKTI, in the epidermis: implications for skin homeostasis.

Fortugno P, Bresciani A, Paolini C, Pazzagli C, El Hachem M, D'Alessio M, Zambruno G
The Journal of investigative dermatology 2011 Nov;131(11):2223-32

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Inhibition of transcription factor specificity protein 1 alters the gene expression profile of keratinocytes leading to upregulation of kallikrein-related peptidases and thymic stromal lymphopoietin.

Bin L, Kim BE, Hall CF, Leach SM, Leung DY
The Journal of investigative dermatology 2011 Nov;131(11):2213-22

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Kallikrein expression and cathelicidin processing are independently controlled in keratinocytes by calcium, vitamin D(3), and retinoic acid.

Morizane S, Yamasaki K, Kabigting FD, Gallo RL
The Journal of investigative dermatology 2010 May;130(5):1297-306