CABT-B11152

antibody from Creative Diagnostics

Targeting: RASA3 GAP1IP4BP, GAPIII

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

CABT-B11152

Provider

Creative Diagnostics

Product name

Mouse anti-Human RASA3 monoclonal antibody, clone 2G22

Antibody type

Monoclonal

Description

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane. [provided by RefSeq, Jul 2008]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2G22

Vial size

50 _g

Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.