AMM03993G

antibody from Leading Biology

Targeting: RASA3 GAP1IP4BP, GAPIII

Western blot (Recommended by provider)

Antibody Data

Product number

AMM03993G

Provider

Leading Biology

Product name

RASA3 Antibody (monoclonal) (M01)

Antibody type

Monoclonal

Description

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

1F11

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.