APR04139G

antibody from Leading Biology

Targeting: UBE2D3 UbcH5C

Western blot (Recommended by provider)

Antibody Data

Product number

APR04139G

Provider

Leading Biology

Product name

UBE2D3 Antibody (C-term)

Antibody type

Polyclonal

Description

The modification of proteins with ubiquitin is animportant cellular mechanism for targeting abnormal or short-livedproteins for degradation. Ubiquitination involves at least threeclasses of enzymes: ubiquitin-activating enzymes, or E1s,ubiquitin-conjugating enzymes, or E2s, and ubiquitin-proteinligases, or E3s. This gene encodes a member of the E2ubiquitin-conjugating enzyme family. This enzyme functions in theubiquitination of the tumor-suppressor protein p53, which isinduced by an E3 ubiquitin-protein ligase. Multiple splicedtranscript variants have been found for this gene, but thefull-length nature of some variants has not been determined.

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.