FNab07152

antibody from FineTest Biotech

Targeting: RBBP6 P2P-R, PACT, SNAMA

Western blot

ELISA

Antibody data

Submit

Validation data

Product number: FNab07152 - Provider product page
Provider: FineTest Biotech
Product name: RBBP6 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome(PubMed:18851979). May play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53; may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth(By similarity). Regulates DNA-replication and the stability of chromosomal common fragile sites(CFSs) in a ZBTB38-and MCM10-dependent manner. Controls ZBTB38 protein stability and abundance via ubiquitination and proteasomal degradation, and ZBTB38 in turn negatively regulates the expression of MCM10 which plays an important role in DNA-replication(PubMed:24726359).
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: retinoblastoma binding protein 6
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

RBBP6 protein structure - FNab07152 shown in red.