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- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
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- Product number
- ABIN1881828 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2) (Center), (AA 372-401) antibody
- Antibody type
- Polyclonal
- Antigen
- This SPTLC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 372-401 amino acids from the Central region of human SPTLC2.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- Center,AA 372-401
- Antibody clone number
- RB42738
- Vial size
- 400 μL
- Concentration
- 0.5 mg/mL
Submitted references Mutations in the SPTLC2 subunit of serine palmitoyltransferase cause hereditary sensory and autonomic neuropathy type I.
Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities.
The essential nature of sphingolipids in plants as revealed by the functional identification and characterization of the Arabidopsis LCB1 subunit of serine palmitoyltransferase.
Rotthier A, Auer-Grumbach M, Janssens K, Baets J, Penno A, Almeida-Souza L, Van Hoof K, Jacobs A, De Vriendt E, Schlotter-Weigel B, Löscher W, Vondráček P, Seeman P, De Jonghe P, Van Dijck P, Jordanova A, Hornemann T, Timmerman V
American journal of human genetics 2010 Oct 8;87(4):513-22
American journal of human genetics 2010 Oct 8;87(4):513-22
Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities.
Han G, Gupta SD, Gable K, Niranjanakumari S, Moitra P, Eichler F, Brown RH Jr, Harmon JM, Dunn TM
Proceedings of the National Academy of Sciences of the United States of America 2009 May 19;106(20):8186-91
Proceedings of the National Academy of Sciences of the United States of America 2009 May 19;106(20):8186-91
The essential nature of sphingolipids in plants as revealed by the functional identification and characterization of the Arabidopsis LCB1 subunit of serine palmitoyltransferase.
Chen M, Han G, Dietrich CR, Dunn TM, Cahoon EB
The Plant cell 2006 Dec;18(12):3576-93
The Plant cell 2006 Dec;18(12):3576-93
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- SPTLC2 Antibody (Center) (ABIN1881828) western blot analysis in HepG2 cell line lysates (35 μg/lane). This demonstrates the SPTLC2 antibody detected the SPTLC2 protein (arrow).
