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- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Flow cytometry [1]
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- Product number
- 311411 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#311411, RRID:AB_493131
- Product name
- LEAF™ Purified anti-human HLA-A,B,C [W6/32]
- Antibody type
- Monoclonal
- Antigen
- HLA-A,B,C
- Description
- MHC class I antigens associated with β2-microglobulin are expressed by all human nucleated cells. MHC class I molecules are involved in presentation of antigens to CD8+ T cells. They play an important role in cell-mediated immune responses and tumor surveillance.
- Reactivity
- Human, Bovine, Feline, Simian
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 50 µg
- Concentration
- 1 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4 °C. This LEAF™ solution contains no preservative; handle under aseptic conditions.
Submitted references Glutaraldehyde treatment of allograft tissue decreases allosensitization after the Norwood procedure.
Copulsing tumor antigen-pulsed dendritic cells with zoledronate efficiently enhance the expansion of tumor antigen-specific CD8+ T cells via Vgamma9gammadelta T cell activation.
IFN-gamma regulated chemokine production determines the outcome of Staphylococcus aureus infection.
Laing BJ, Ross DB, Meyer SR, Campbell P, Halpin AM, West LJ, Rebeyka IM
The Journal of thoracic and cardiovascular surgery 2010 Jun;139(6):1402-8
The Journal of thoracic and cardiovascular surgery 2010 Jun;139(6):1402-8
Copulsing tumor antigen-pulsed dendritic cells with zoledronate efficiently enhance the expansion of tumor antigen-specific CD8+ T cells via Vgamma9gammadelta T cell activation.
Takahara M, Miyai M, Tomiyama M, Mutou M, Nicol AJ, Nieda M
Journal of leukocyte biology 2008 Mar;83(3):742-54
Journal of leukocyte biology 2008 Mar;83(3):742-54
IFN-gamma regulated chemokine production determines the outcome of Staphylococcus aureus infection.
McLoughlin RM, Lee JC, Kasper DL, Tzianabos AO
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 15;181(2):1323-32
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 15;181(2):1323-32
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes stained with LEAF™ purified W6/32, followed by anti-mouse IgG FITC
- Conjugate
- Unconjugated
