ABIN350419

antibody from antibodies-online

Targeting: CACNA1F AIED, Cav1.4, CORDX3, CSNB2, CSNB2A, CSNBX2, JM8, JMC8, OA2

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN350419

Provider

antibodies-online

Proper citation

Antibodies-Online Cat#ABIN350419, RRID:AB_10786765

Product name

anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) (N-Term) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide from the n-terminal region of KCNMB1 (Maxi K channel subunit beta-1) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and mouse.

Reactivity

Human

Host

Rabbit

Epitope

N-Term

Isotype

IgG

Vial size

500 μg

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.

Handling

Avoid freeze and thaw cycles.

References

Submitted references

Complete sequencing and characterization of 21,243 full-length human cDNAs.

Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nature genetics 2004 Jan;36(1):40-5

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Gain-of-function mutation in the KCNMB1 potassium channel subunit is associated with low prevalence of diastolic hypertension.

Fernández-Fernández JM, Tomás M, Vázquez E, Orio P, Latorre R, Sentí M, Marrugat J, Valverde MA
The Journal of clinical investigation 2004 Apr;113(7):1032-9

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Calcium-activated potassium channel expression in human myometrium: effect of pregnancy.

Mazzone JN, Kaiser RA, Buxton IL
Proceedings of the Western Pharmacology Society 2002;45:184-6

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A calcium switch for the functional coupling between alpha (hslo) and beta subunits (KV,Ca beta) of maxi K channels.

Meera P, Wallner M, Jiang Z, Toro L
FEBS letters 1996 Mar 11;382(1-2):84-8

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Cloning, expression, and distribution of a Ca(2+)-activated K+ channel beta-subunit from human brain.

Tseng-Crank J, Godinot N, Johansen TE, Ahring PK, Strøbaek D, Mertz R, Foster CD, Olesen SP, Reinhart PH
Proceedings of the National Academy of Sciences of the United States of America 1996 Aug 20;93(17):9200-5