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- Antibody Data
- Antigen structure
- References [19]
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- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- H00085377-B01P - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00085377-B01P, RRID:AB_2143767
- Product name
- Mouse Polyclonal MICALL1 Antibody
- Antibody type
- Polyclonal
- Description
- Protein A purified. MICAL-L1 - MICAL-like 1,
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.05 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references GRAF2, WDR44, and MICAL1 mediate Rab8/10/11-dependent export of E-cadherin, MMP14, and CFTR ΔF508.
Diverse Papillomavirus Types Induce Endosomal Tubulation.
Rab10 regulates tubular endosome formation through KIF13A and KIF13B motors.
Vesicular trafficking plays a role in centriole disengagement and duplication.
Human Papillomavirus 16 Infection Induces VAP-Dependent Endosomal Tubulation.
Sphingolipids inhibit endosomal recycling of nutrient transporters by inactivating ARF6.
Analysis of novel endosome-to-Golgi retrieval genes reveals a role for PLD3 in regulating endosomal protein sorting and amyloid precursor protein processing.
Endocytic turnover of Rab8 controls cell polarization.
EHD3 Protein Is Required for Tubular Recycling Endosome Stabilization, and an Asparagine-Glutamic Acid Residue Pair within Its Eps15 Homology (EH) Domain Dictates Its Selective Binding to NPF Peptides.
Novel functions for the endocytic regulatory proteins MICAL-L1 and EHD1 in mitosis.
Diacylglycerol kinase α regulates tubular recycling endosome biogenesis and major histocompatibility complex class I recycling.
Rab35 promotes the recruitment of Rab8, Rab13 and Rab36 to recycling endosomes through MICAL-L1 during neurite outgrowth.
Differential roles of C-terminal Eps15 homology domain proteins as vesiculators and tubulators of recycling endosomes.
Cooperation of MICAL-L1, syndapin2, and phosphatidic acid in tubular recycling endosome biogenesis.
Rab35 establishes the EHD1-association site by coordinating two distinct effectors during neurite outgrowth.
cPLA2α and EHD1 interact and regulate the vesiculation of cholesterol-rich, GPI-anchored, protein-containing endosomes.
MICAL-L1 is a tubular endosomal membrane hub that connects Rab35 and Arf6 with Rab8a.
Collapsin response mediator protein-2 (Crmp2) regulates trafficking by linking endocytic regulatory proteins to dynein motors.
MICAL-L1 links EHD1 to tubular recycling endosomes and regulates receptor recycling.
Lucken-Ardjomande Häsler S, Vallis Y, Pasche M, McMahon HT
The Journal of cell biology 2020 May 4;219(5)
The Journal of cell biology 2020 May 4;219(5)
Diverse Papillomavirus Types Induce Endosomal Tubulation.
Siddiqa A, Massimi P, Pim D, Banks L
Frontiers in cellular and infection microbiology 2019;9:175
Frontiers in cellular and infection microbiology 2019;9:175
Rab10 regulates tubular endosome formation through KIF13A and KIF13B motors.
Etoh K, Fukuda M
Journal of cell science 2019 Feb 19;132(5)
Journal of cell science 2019 Feb 19;132(5)
Vesicular trafficking plays a role in centriole disengagement and duplication.
Xie S, Reinecke JB, Farmer T, Bahl K, Yeow I, Nichols BJ, McLamarrah TA, Naslavsky N, Rogers GC, Caplan S
Molecular biology of the cell 2018 Nov 1;29(22):2622-2631
Molecular biology of the cell 2018 Nov 1;29(22):2622-2631
Human Papillomavirus 16 Infection Induces VAP-Dependent Endosomal Tubulation.
Siddiqa A, Massimi P, Pim D, Broniarczyk J, Banks L
Journal of virology 2018 Mar 15;92(6)
Journal of virology 2018 Mar 15;92(6)
Sphingolipids inhibit endosomal recycling of nutrient transporters by inactivating ARF6.
Finicle BT, Ramirez MU, Liu G, Selwan EM, McCracken AN, Yu J, Joo Y, Nguyen J, Ou K, Roy SG, Mendoza VD, Corrales DV, Edinger AL
Journal of cell science 2018 Jun 25;131(12)
Journal of cell science 2018 Jun 25;131(12)
Analysis of novel endosome-to-Golgi retrieval genes reveals a role for PLD3 in regulating endosomal protein sorting and amyloid precursor protein processing.
Mukadam AS, Breusegem SY, Seaman MNJ
Cellular and molecular life sciences : CMLS 2018 Jul;75(14):2613-2625
Cellular and molecular life sciences : CMLS 2018 Jul;75(14):2613-2625
Endocytic turnover of Rab8 controls cell polarization.
Vidal-Quadras M, Holst MR, Francis MK, Larsson E, Hachimi M, Yau WL, Peränen J, Martín-Belmonte F, Lundmark R
Journal of cell science 2017 Mar 15;130(6):1147-1157
Journal of cell science 2017 Mar 15;130(6):1147-1157
EHD3 Protein Is Required for Tubular Recycling Endosome Stabilization, and an Asparagine-Glutamic Acid Residue Pair within Its Eps15 Homology (EH) Domain Dictates Its Selective Binding to NPF Peptides.
Bahl K, Xie S, Spagnol G, Sorgen P, Naslavsky N, Caplan S
The Journal of biological chemistry 2016 Jun 24;291(26):13465-78
The Journal of biological chemistry 2016 Jun 24;291(26):13465-78
Novel functions for the endocytic regulatory proteins MICAL-L1 and EHD1 in mitosis.
Reinecke JB, Katafiasz D, Naslavsky N, Caplan S
Traffic (Copenhagen, Denmark) 2015 Jan;16(1):48-67
Traffic (Copenhagen, Denmark) 2015 Jan;16(1):48-67
Diacylglycerol kinase α regulates tubular recycling endosome biogenesis and major histocompatibility complex class I recycling.
Xie S, Naslavsky N, Caplan S
The Journal of biological chemistry 2014 Nov 14;289(46):31914-26
The Journal of biological chemistry 2014 Nov 14;289(46):31914-26
Rab35 promotes the recruitment of Rab8, Rab13 and Rab36 to recycling endosomes through MICAL-L1 during neurite outgrowth.
Kobayashi H, Etoh K, Ohbayashi N, Fukuda M
Biology open 2014 Aug 1;3(9):803-14
Biology open 2014 Aug 1;3(9):803-14
Differential roles of C-terminal Eps15 homology domain proteins as vesiculators and tubulators of recycling endosomes.
Cai B, Giridharan SS, Zhang J, Saxena S, Bahl K, Schmidt JA, Sorgen PL, Guo W, Naslavsky N, Caplan S
The Journal of biological chemistry 2013 Oct 18;288(42):30172-80
The Journal of biological chemistry 2013 Oct 18;288(42):30172-80
Cooperation of MICAL-L1, syndapin2, and phosphatidic acid in tubular recycling endosome biogenesis.
Giridharan SS, Cai B, Vitale N, Naslavsky N, Caplan S
Molecular biology of the cell 2013 Jun;24(11):1776-90, S1-15
Molecular biology of the cell 2013 Jun;24(11):1776-90, S1-15
Rab35 establishes the EHD1-association site by coordinating two distinct effectors during neurite outgrowth.
Kobayashi H, Fukuda M
Journal of cell science 2013 Jun 1;126(Pt 11):2424-35
Journal of cell science 2013 Jun 1;126(Pt 11):2424-35
cPLA2α and EHD1 interact and regulate the vesiculation of cholesterol-rich, GPI-anchored, protein-containing endosomes.
Cai B, Caplan S, Naslavsky N
Molecular biology of the cell 2012 May;23(10):1874-88
Molecular biology of the cell 2012 May;23(10):1874-88
MICAL-L1 is a tubular endosomal membrane hub that connects Rab35 and Arf6 with Rab8a.
Rahajeng J, Giridharan SS, Cai B, Naslavsky N, Caplan S
Traffic (Copenhagen, Denmark) 2012 Jan;13(1):82-93
Traffic (Copenhagen, Denmark) 2012 Jan;13(1):82-93
Collapsin response mediator protein-2 (Crmp2) regulates trafficking by linking endocytic regulatory proteins to dynein motors.
Rahajeng J, Giridharan SS, Naslavsky N, Caplan S
The Journal of biological chemistry 2010 Oct 15;285(42):31918-22
The Journal of biological chemistry 2010 Oct 15;285(42):31918-22
MICAL-L1 links EHD1 to tubular recycling endosomes and regulates receptor recycling.
Sharma M, Giridharan SS, Rahajeng J, Naslavsky N, Caplan S
Molecular biology of the cell 2009 Dec;20(24):5181-94
Molecular biology of the cell 2009 Dec;20(24):5181-94
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: MICALL1 Antibody [H00085377-B01P] - Analysis of MICALL1 expression in transfected 293T cell line by MICALL1 polyclonal antibody. Lane 1: MICAL-L1 transfected lysate(94.93 KDa). Lane 2: Non-transfected lysate.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: MICALL1 Antibody [H00085377-B01P] - Analysis of MICALL1 expression in HepG2.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MICALL1 Antibody [H00085377-B01P] - IHC staining of MICALL1 in human prostate cancer using DAB with hematoxylin counterstain.
